Alzheimer's Disease Clinical Trials

45 trials recruiting in Canada.

Brain & Nervous System

Recruiting Drug Device Behavioral Older adults Healthy volunteers

24 trials

Testing Trontinemab against a placebo for Alzheimer's disease

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One site, in Toronto

Official title: A Study of Trontinemab in Cognitively Unimpaired Individuals at Risk for Progression to Symptomatic Alzheimer's Disease

Alzheimer's Disease · Hoffmann-La Roche

Testing Remternetug (SC) against a placebo for alzheimers disease

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Sites in Québec, Toronto and 2 more cities

RecruitingPHASE2

Official title: A Study of Potential Disease Modifying Treatments in Individuals at Risk for or With a Type of Early Onset AD Caused by a Genetic Mutation

Alzheimers Disease · Washington University School of Medicine

Testing Remternetug against a placebo for alzheimers disease

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Sites in Québec, Toronto and 2 more cities

RecruitingPHASE2

Official title: A Study of a Potential Disease Modifying Treatment in Individuals at Risk for or With a Type of Early Onset AD Caused by a Genetic Mutation

Alzheimers Disease · Washington University School of Medicine

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Testing KarXT with KarX-EC for alzheimer disease

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Sites in Toronto, Hamilton and 2 more cities

RecruitingPHASE3

Official title: A Study to Evaluate the Long-term Efficacy and Safety of KarXT + KarX-EC for Agitation in Alzheimer's Disease (ADAGIO-3)

Alzheimer Disease · Bristol-Myers Squibb

Testing KarXT with KarX-EC against a placebo for Alzheimer's disease

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Sites in Greenfield Park, Halifax and 6 more cities

RecruitingPHASE3

Official title: A Study to Evaluate the Efficacy and Safety of KarXT + KarX-EC for Cognitive Impairment in Alzheimer's Disease

Alzheimer's Disease · Bristol-Myers Squibb

Testing MK-2214 against a placebo for early Alzheimer's disease

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Sites in Toronto, Montreal and 1 more city

RecruitingPHASE2

Official title: A Clinical Study of MK-2214 in People With Early Alzheimer's Disease (MK-2214-004)

Early Alzheimer's Disease · Merck Sharp & Dohme LLC

Testing Trontinemab against a placebo for alzheimers disease

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Sites in Toronto, Montreal and 3 more cities

RecruitingPHASE3

Official title: A Study of Trontinemab in Participants With Early Symptomatic Alzheimer's Disease

Alzheimers Disease · Hoffmann-La Roche

Testing ALN-5288 against a placebo for Alzheimer's disease

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Sites in Toronto, Montreal and 1 more city

RecruitingPHASE1

Official title: A Study to Evaluate ALN-5288 in Patients With Alzheimer's Disease

Alzheimer's Disease · Alnylam Pharmaceuticals

Comparing Methylphenidate with intermittent theta burst stimulation for alzheimer s disease

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One site, in Toronto

RecruitingPHASE2

Official title: Combined Brain Stimulation and Methylphenidate Treatment for Apathy in Dementia

Alzheimer s Disease · Sunnybrook Health Sciences Centre

Testing ALN-APP against a placebo for early-onset alzheimer disease

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Sites in Montreal and Toronto

RecruitingPHASE1

Official title: A Study to Evaluate the Safety and Tolerability of ALN-APP in Patients With EOAD

Early-Onset Alzheimer Disease · Alnylam Pharmaceuticals

Comparing methylphenidate with rTMS for alzheimer disease

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One site, in Toronto

Recruiting

Official title: rTMS for Apathy Clinical Trial

Alzheimer Disease · Sunnybrook Health Sciences Centre

Testing Xanomeline/Trospium Chloride with Xanomeline Enteric against a placebo for alzheimer disease

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Sites in London, Toronto and 3 more cities

RecruitingPHASE3

Official title: A Phase 3 Study to Evaluate the Safety and Efficacy of KarXT + KarX-EC for the Treatment of Agitation Associated With Alzheimer's Disease (ADAGIO-1)

Alzheimer Disease · Bristol-Myers Squibb

Testing GSK4527226 for Alzheimer's disease

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Sites in Greenfield Park, Ottawa and 3 more cities

RecruitingPHASE2

Official title: Open-label Extension Study in Participants With Early Alzheimer's Disease

Alzheimer's Disease · GlaxoSmithKline

Testing Trontinemab against a placebo for alzheimers disease

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Sites in Toronto, Halifax and 5 more cities

RecruitingPHASE3

Official title: A Clinical Trial of Trontinemab in Participants With Early Symptomatic Alzheimer's Disease

Alzheimers Disease · Hoffmann-La Roche

Testing Daridorexant against a placebo for alzheimer disease (AD)

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One site, in Montreal

RecruitingPHASE2

Official title: Daridorexant for Alzheimer Disease Prevention

Alzheimer Disease (AD) · Douglas Mental Health University Institute

Testing ARO-MAPT-SC against a placebo for alzheimer disease

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Sites in East York and Toronto

RecruitingPHASE1

Official title: Study of ARO-MAPT-SC in Healthy Participants and Participants With Early Alzheimer's Disease

Alzheimer Disease · Arrowhead Pharmaceuticals

Testing EXV-802 against a placebo for agitation associated with Alzheimer's disease dementia

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Sites in North York, Peterborough and 1 more city

RecruitingPHASE2

Official title: Safety and Efficacy of EXV-802 and EXV-801 in the Treatment of Agitation in Alzheimer's Disease Dementia

Agitation Associated With Alzheimer's Disease Dementia · Exciva GmbH

Testing KarXT for psychosis associated with Alzheimer's disease

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Sites in Calgary, Hamilton and 3 more cities

RecruitingPHASE3

Official title: Open-Label Extension Study to Assess the Long-Term Safety and Tolerability of KarXT in Subjects With Psychosis Associated With Alzheimer's Disease (ADEPT-3)

Psychosis Associated With Alzheimer's Disease · Karuna Therapeutics, Inc., a Bristol Myers Squibb company

Testing KarXT against a placebo for psychosis associated with Alzheimer's disease

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Sites in Calgary, Hamilton and 4 more cities

RecruitingPHASE3

Official title: A Study to Assess Efficacy and Safety of KarXT for the Treatment of Psychosis Associated With Alzheimer's Disease (ADEPT-2)

Psychosis Associated With Alzheimer's Disease · Karuna Therapeutics, Inc., a Bristol Myers Squibb company

Testing ML-007C-MA against a placebo for psychosis associated with Alzheimer's disease

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Sites in Brampton, Lévis and 2 more cities

RecruitingPHASE2

Official title: A Study to Assess the Efficacy and Safety of ML-007C-MA for the Treatment of Alzheimer's Disease Psychosis

Psychosis Associated With Alzheimer's Disease · MapLight Therapeutics

Testing KarXT with KarX-EC against a placebo for alzheimer disease

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Sites in Montreal, Toronto and 1 more city

RecruitingPHASE3

Official title: A Study to Evaluate Safety and Efficacy of KarXT + KarX-EC as a Treatment for Psychosis Associated With Alzheimer's Disease (ADEPT-5)

Alzheimer Disease · Bristol-Myers Squibb

Testing Nabilone against a placebo for alzheimer disease

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Sites in Toronto, Calgary and 2 more cities

RecruitingPHASE3

Official title: Nabilone for Agitation Blinded Intervention Trial

Alzheimer Disease · Sunnybrook Health Sciences Centre

Testing IGC-AD1-Active against a placebo for alzheimer disease

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Sites in Hamilton, Montreal and 2 more cities

RecruitingPHASE2

Official title: Clinical Trial on Agitation in Alzheimer's Dementia

Alzheimer Disease · IGC Pharma, LLC

Testing CBD for alzheimer disease

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Sites in Toronto, Calgary and 2 more cities

RecruitingPHASE2

Official title: Cannabidiol Medication Intervention Trial

Alzheimer Disease · Sunnybrook Health Sciences Centre

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Concord provides information support only. Trial listings come from public registries; eligibility is always determined by the trial site and your care team.