Atrial Fibrillation Clinical Trials

28 trials recruiting in Canada.

Heart & Circulation

Recruiting Drug Device Behavioral Older adults Healthy volunteers

28 trials

Comparing REGN7508 with Apixaban for atrial fibrillation (AF)

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There are 2 groups in this study. Group A receives REGN7508 and Placebo. Group B, the comparison group, receives Apixaban and Placebo.

Sites in Hamilton, Longueuil and 1 more city

Phase 3
2 groups
Sites in Hamilton, Sherbrooke and 1 more city
Recruiting

Official title: Stroke and Systemic Embolism Prevention in Adult Participants With Atrial Fibrillation

Atrial Fibrillation (AF) · Regeneron Pharmaceuticals

Comparing 3 approaches for atrial fibrillation (AF)

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There are 3 groups in this study. Group A receives REGN7508. Group B receives REGN9933. Group C, the comparison group, receives Apixaban.

Sites in Hamilton, Sherbrooke and 12 more cities

Phase 2
3 groups
Sites in Edmonton, Victoria and 12 more cities
Recruiting

Official title: Safety in Adult Participants With Atrial Fibrillation Who Are Treated With Anticoagulation

Atrial Fibrillation (AF) · Regeneron Pharmaceuticals

Testing PKN605 against a placebo for atrial fibrillation

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There are 3 groups in this study. Groups A and B receive PKN605. Group C, the placebo group, receives Placebo.

Sites in Montreal, Toronto and 8 more cities

Phase 2
3 groups
Sites in Calgary, Vancouver and 8 more cities
Recruiting

Official title: A Study to Investigate the Efficacy, Safety, Tolerability and Pharmacokinetics of PKN605 in Participants With Atrial Fibrillation

Atrial Fibrillation · Novartis Pharmaceuticals

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Testing Catheter-based renal artery electrical for atrial fibrillation (paroxysmal)

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Everyone in this study is in one group and receives Catheter-based renal artery electrical stimulation (as a feasibility assessment for renal denervation).

One site, in London

1 group
One site, in London
Recruiting

Official title: Renal Denervation in Patients With Atrial Fibrillation and Hypertension

Atrial Fibrillation (Paroxysmal) · Pavel Antiperovitch

Testing Left Posterior Pericardiotomy for atrial fibrillation

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There are 2 groups in this study. Group A receives Left Posterior Pericardiotomy. Group B receives no study treatment and is followed for comparison.

Sites in Montreal, Halifax and 2 more cities

2 groups
Sites in Halifax, Hamilton and 2 more cities
Recruiting

Official title: Pericardiotomy in Cardiac Surgery

Atrial Fibrillation · Population Health Research Institute

Testing Catheter Ablation for Atrial for atrial fibrillation (AF)

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There are 2 groups in this study. Group A, the comparison group, receives Catheter Ablation for Atrial Fibrillation. Group B, the comparison group, receives Rate Control Medications (beta-blockers, calcium channel blockers, digoxin).

Sites in Halifax, Hamilton and 2 more cities

2 groups
Sites in Halifax, Hamilton and 2 more cities
Recruiting

Official title: Treating Atrial Fibrillation in Heart Failure With Preserved Ejection Fraction: Ablation or Medication

Atrial Fibrillation (AF) · Nova Scotia Health Authority

Testing REGN7508 against a placebo for atrial fibrillation (AF)

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There are 3 groups in this study. Group A receives REGN7508. Group B receives REGN9933. Group C, the placebo group, receives Placebo.

One site, in Hamilton

Phase 3
3 groups
One site, in Hamilton
Recruiting

Official title: Stroke and Systemic Embolism Prevention in Adult Participants With Atrial Fibrillation for Whom Oral Anticoagulation is Unsuitable

Atrial Fibrillation (AF) · Regeneron Pharmaceuticals

Testing Isolator® Synergy™ EnCompass® Ablation for post operative atrial fibrillation

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There are 2 groups in this study. Group A receives Isolator® Synergy™ EnCompass® Ablation System and AtriClip® LAA Exclusion System. Group B receives no study treatment and is followed for comparison.

Sites in Hamilton, London and 2 more cities

2 groups
Sites in New Westminster, Hamilton and 2 more cities
Recruiting

Official title: BoxX-NoAF Clinical Trial

Post Operative Atrial Fibrillation · AtriCure, Inc.

Testing Etripamil against a placebo for atrial fibrillation

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There are 2 groups in this study. Group A, the placebo group, receives Placebo. Group B receives Etripamil.

One site, in Montreal

Phase 3
2 groups
One site, in Montreal
Recruiting

Official title: ReVeRA-301: Etripamil in Atrial Fibrillation Phase 3

Atrial Fibrillation · Milestone Pharmaceuticals Inc.

Testing Surgical Atrial Fibrillation Ablation for atrial fibrillation

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There are 2 groups in this study. Group A receives Surgical Atrial Fibrillation Ablation. Group B receives no study treatment and is followed for comparison.

One site, in Hamilton

2 groups
One site, in Hamilton
Recruiting

Official title: Surgical Ablation of AF Efficacy Trial

Atrial Fibrillation · Population Health Research Institute

Comparing Apixaban with Rivaroxaban for atrial fibrillation

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There are 2 groups in this study. Group A, the comparison group, receives Apixaban. Group B, the comparison group, receives Rivaroxaban.

Sites in Ottawa, Gatineau and 5 more cities

Phase 4
2 groups
Sites in Victoria, Halifax and 5 more cities
Recruiting

Official title: COmparison of Bleeding Risk Between Rivaroxaban and Apixaban in Patients With Atrial Fibrillation

Atrial Fibrillation · Ottawa Hospital Research Institute

Testing WATCHMAN device for atrial fibrillation

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There are 2 groups in this study. Group A receives WATCHMAN device. Group B receives no study treatment and is followed for comparison.

Sites in Toronto, Hamilton and 15 more cities

2 groups
Sites in Calgary, Vancouver and 15 more cities
Recruiting

Official title: The Fourth Left Atrial Appendage Occlusion Study

Atrial Fibrillation · Hamilton Health Sciences Corporation

Comparing 12-lead ECG monitoring device (MiRTLE with 3-lead ECG gating system for atrial fibrillation

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There are 2 groups in this study. Group A receives 12-lead ECG monitoring device (MiRTLE Medical). Group B, the comparison group, receives 3-lead ECG gating system.

One site, in Toronto

2 groups
One site, in Toronto
Recruiting

Official title: Evaluation of MRI-conditional 12-lead ECG

Atrial Fibrillation · Dr. Graham Wright

Testing Dynamic fluoroscopy for atrial fibrillation

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Everyone in this study is in one group and receives Dynamic fluoroscopy.

One site, in Montreal

1 group
One site, in Montreal
Recruiting

Official title: Diaphragmatic Evaluation by Fluoroscopy to Identify Phrenic Nerve Dysfunction Related to Electroporation

Atrial Fibrillation · French Cardiology Society

Comparing 4 approaches for atrial fibrillation (AF)

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There are 4 groups in this study. Groups A, B, C and D, the comparison group, receive one or more of: PAUSE Perioperative DOAC Management and ASRA Perioperative DOAC Management.

Sites in Hamilton, Ottawa and 2 more cities

4 groups
Sites in Winnipeg, Hamilton and 2 more cities
Recruiting

Official title: Perioperative Anticoagulant Use for Surgery Evaluation -2 (PAUSE-2) Study Patients Receiving a Direct Oral Anticoagulant (DOACs-Dabigatran, Rivaroxaban, Apixaban or Edoxaban) and Needing Elective High-Bleed-Risk Surgery or an Invasive Procedure

Atrial Fibrillation (AF) · McMaster University

Testing Catheter Ablation for atrial fibrillation (AF)

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There are 2 groups in this study. Group A receives no study treatment and is followed for comparison. Group B receives Catheter Ablation.

One site, in Halifax

2 groups
One site, in Halifax
Recruiting

Official title: Cryoballoon/Radiofrequency/Pulsed Field Ablation of Atrial Fibrillation Versus Medical Treatment for Heart

Atrial Fibrillation (AF) · University College, London

Testing Early atrial fibrillation ablation for atrial fibrillation

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There are 2 groups in this study. Group A receives Early atrial fibrillation ablation. Group B receives Usual Care.

One site, in Multiple Locations

2 groups
Recruiting

Official title: Early Atrial Fibrillation Ablation for Stroke Prevention in Patients With High Comorbidity Burden (EASThigh-AFNET 11)

Atrial Fibrillation · Atrial Fibrillation Network

Comparing Medication with Pace and Ablate for atrial fibrillation

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There are 2 groups in this study. Group A, the comparison group, receives Medication. Group B receives Pace and Ablate.

Sites in Montreal, Halifax and 9 more cities

2 groups
Sites in Victoria, Halifax and 9 more cities
Recruiting

Official title: RAFT - Pace &Ablate

Atrial Fibrillation · Habib Khan

Testing Amiodarone Hydrochloride for atrial fibrillation new onset

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There are 2 groups in this study. Group A, the comparison group, receives Amiodarone Hydrochloride 200 MG. Group B receives no study treatment and is followed for comparison.

Sites in Hamilton and Toronto

Phase 3
2 groups
Sites in Hamilton and Toronto
Recruiting

Official title: Short Term Anti-aRrhythmic Therapy for Post-Operative AF in Cardiac Surgery Patients Pilot Trial

Atrial Fibrillation New Onset · Population Health Research Institute

Testing Abelacimab against a placebo for atrial fibrillation (AF)

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There are 2 groups in this study. Group A receives Abelacimab. Group B, the placebo group, receives Placebo.

Sites in Toronto, Hamilton and 19 more cities

Phase 3
2 groups
Sites in Mira Road, Cambridge and 18 more cities
Recruiting

Official title: Study to evaLuate the effIcacy and Safety of abeLacimab in High-risk Patients With Atrial Fibrillation Who Have Been Deemed Unsuitable for Oral antiCoagulation (LILAC-TIMI 76)

Atrial Fibrillation (AF) · Anthos Therapeutics, Inc.

Testing PVI-PLUS ARM, INTERVENTIONAL ARM for atrial fibrillation

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There are 2 groups in this study. Group A, the comparison group, receives PVI-ONLY, CONTROL ARM. Group B receives PVI-PLUS ARM, INTERVENTIONAL ARM.

Sites in Montreal and Ottawa

2 groups
Sites in Ottawa and Montreal
Recruiting

Official title: Randomized Controlled Trial- Ablation Strategy for Paroxysmal Atrial Fibrillation - Trigger and Substrate Guided Wide Area Radiofrequency Ablation Compared to Pulsed Field Ablation Pulmonary Vein Isolation

Atrial Fibrillation · Ottawa Heart Institute Research Corporation

Comparing standard care + moderate-intensity with standard care + high-intensity interval for atrial fibrillation

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There are 3 groups in this study. Group A receives no study treatment and is followed for comparison. Group B receives standard care + moderate-intensity continuous exercise training. Group C receives standard care + high-intensity interval training.

Sites in London and Ottawa

3 groups
Sites in London and Ottawa
Recruiting

Official title: Exercise Training in Patients With Persistent or Permanent Atrial Fibrillation

Atrial Fibrillation · Ottawa Heart Institute Research Corporation

Testing Cardiac computed tomography angiography for atrial fibrillation (AF)

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There are 2 groups in this study. Group A, the comparison group, receives Standard of care management. Group B receives Cardiac computed tomography angiography.

Sites in Ottawa and Toronto

2 groups
Sites in Ottawa and Toronto
Recruiting

Official title: Left Atrial Imaging Prior to Cardioversion: Leveraging Computed Tomography to Rule Out Thrombus in The Emergency Department (LA CLOTTED)

Atrial Fibrillation (AF) · Ottawa Heart Institute Research Corporation

Comparing Electronic patient decision aid with Information for atrial fibrillation

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There are 2 groups in this study. Group A receives Electronic patient decision aid. Group B, the comparison group, receives Information.

2 sites in Calgary

2 groups
2 sites in Calgary
Recruiting

Official title: RAPID AFib Decision Aid for Stroke Prevention in Atrial Fibrillation

Atrial Fibrillation · University of Calgary

Testing Vine Filter for atrial fibrillation

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There are 2 groups in this study. Group A receives Vine Filter. Group B receives no study treatment and is followed for comparison.

Sites in Hamilton and London

2 groups
Sites in Hamilton and London
Recruiting

Official title: Carotid Implants for PreveNtion of STrokE ReCurrEnce From Large Vessel Occlusion in Atrial Fibrillation Patients Treated With Oral Anticoagulation

Atrial Fibrillation · Javelin Medical

Comparing Anterolateral electrode position with Anteroposterior electrode position for atrial fibrillation

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There are 2 groups in this study. Group A, the comparison group, receives one or more of: Anterolateral electrode position and Manual pressure. Group B, the comparison group, receives one or more of: Anteroposterior electrode position and Manual pressure.

Sites in Hamilton, Montreal and 2 more cities

2 groups
Sites in Hamilton, Toronto and 2 more cities
Recruiting

Official title: Anteroposterior Versus Anterolateral Electrode Position for Electrical Cardioversion of Atrial Fibrillation

Atrial Fibrillation · McMaster University

Testing Electrical cardioversion against a placebo for atrial fibrillation

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There are 2 groups in this study. Group A receives Electrical cardioversion. Group B, the sham group, receives Sham electrical cardioversion.

Sites in Newmarket and Ottawa

2 groups
Sites in Newmarket and Ottawa
Recruiting

Official title: QOL Improvement After Cardioversion of Persistent AF (QOL-CAFRCT)

Atrial Fibrillation · Ottawa Heart Institute Research Corporation

Comparing Antiplatelet-only strategy with Oral Anticoagulant plus background for atrial fibrillation

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There are 2 groups in this study. Group A, the comparison group, receives Antiplatelet-only strategy. Group B, the comparison group, receives Oral Anticoagulant plus background antiplatelet therapy.

Sites in Montreal, Toronto and 4 more cities

Phase 3
2 groups
Sites in Edmonton, London and 4 more cities
Recruiting

Official title: Anticoagulation for New-Onset Post-Operative Atrial Fibrillation After CABG

Atrial Fibrillation · Icahn School of Medicine at Mount Sinai

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Concord provides information support only. Trial listings come from public registries; eligibility is always determined by the trial site and your care team.