Hypertension Clinical Trials

17 trials recruiting in Canada.

Heart & Circulation

Recruiting Drug Device Behavioral Older adults Healthy volunteers

17 trials

Testing Baxdrostat/dapagliflozin against a placebo for chronic kidney disease and hypertension

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There are 2 groups in this study. Group A receives Baxdrostat/dapagliflozin. Group B, the placebo group, receives Placebo/dapagliflozin.

Sites in Montreal, Toronto and 13 more cities

Phase 3
2 groups
Sites in Edmonton, Surrey and 13 more cities
Recruiting

Official title: A Phase III Renal Outcomes and Cardiovascular Mortality Study to Investigate the Efficacy and Safety of Baxdrostat in Combination With Dapagliflozin in Participants With Chronic Kidney Disease and High Blood Pressure

Chronic Kidney Disease and Hypertension · AstraZeneca

Testing Sotatercept for pulmonary artery hypertension

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Everyone in this study is in one group and receives Sotatercept.

One site, in Edmonton

Phase 4
1 group
One site, in Edmonton
Recruiting

Official title: Sotatercept in Pulmonary Arterial Hypertension

Pulmonary Artery Hypertension · University of Alberta

Comparing Empagliflozin with Ranolazine for pulmonary hypertension

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There are 3 groups in this study. Group A receives Empagliflozin. Group B receives Ranolazine. Group C receives no study treatment and is followed for comparison.

Sites in Calgary, Edmonton and 3 more cities

Phase 2
3 groups
Sites in Calgary, Edmonton and 3 more cities
Recruiting

Official title: Feasibility Trial for a Right Ventricular Failure Platform Trial

Pulmonary Hypertension · University of Alberta

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Testing L606 against a placebo for pulmonary hypertension due to lung disease (disorder)

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There are 2 groups in this study. Group A receives L606. Group B, the placebo group, receives Placebo.

One site, in Calgary

Phase 3
2 groups
One site, in Calgary
Recruiting

Official title: A Phase 3 Study to Evaluate the Safety and Efficacy L606 in Participants With PH-ILD

Pulmonary Hypertension Due to Lung Disease (Disorder) · Liquidia Technologies, Inc.

Testing Seralutinib with Gereic Dry Powder Inhaler for pulmonary arterial hypertension

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Everyone in this study receives Seralutinib, together with one or more of: Gereic Dry Powder Inhaler.

Sites in Calgary, London and 2 more cities

Phase 3
1 group
Sites in Calgary, London and 2 more cities
Recruiting

Official title: Open-label Extension Study of Seralutinib in Adult Subjects With PAH (PROSERA-EXT)

Pulmonary Arterial Hypertension · Gossamer Bio USA, Inc.

Testing ROC-101 for pulmonary arterial hypertension (PAH)

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Everyone in this study is in one group and receives ROC-101.

Sites in Calgary and London

Phase 2
1 group
Sites in Calgary and London
Recruiting

Official title: A Study of ROC-101 in Patients With Pulmonary Arterial Hypertension (PAH) and Pulmonary Hypertension Associated With Interstitial Lung Disease (ILD-PH) (ROCSTAR STUDY)

Pulmonary Arterial Hypertension (PAH) · AllRock Bio, Inc.

Comparing Squegg 4-Week Isometric Handgrip with Zona Plus 4-Week Isometric Handgrip for hypertension

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There are 2 groups in this study. Group A, the comparison group, receives Squegg 4-Week Isometric Handgrip Exercise Intervention. Group B, the comparison group, receives Zona Plus 4-Week Isometric Handgrip Exercise Intervention.

2 sites in Hamilton

2 groups
2 sites in Hamilton
Recruiting

Official title: Feasibility of a Community-Integrated Isometric Handgrip Exercise Program and Its Preliminary Effects on Blood Pressure and Cognitive Function in Older Adults

Hypertension · McMaster University

Testing PET/MR with 18F-FDG for pulmonary hypertension

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Everyone in this study is in one group and receives PET/MR with 18F-FDG.

One site, in Toronto

1 group
One site, in Toronto
Recruiting

Official title: PET/MR Pre- and Post Radiotherapy for Cardiopulmonary Dysfunction Evaluation

Pulmonary Hypertension · University Health Network, Toronto

Testing Sotatercept for pulmonary arterial hypertension

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Everyone in this study is in one group and receives Sotatercept.

Sites in Calgary, Edmonton and 1 more city

Phase 3
1 group
Sites in Calgary, Edmonton and 1 more city
Recruiting

Official title: A Clinical Study of Sotatercept (MK-7962) in People With Pulmonary Arterial Hypertension (MK-7962-038)

Pulmonary Arterial Hypertension · Merck Sharp & Dohme LLC

Testing Physical activity for hypertension, resistant to conventional therapy

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There are 2 groups in this study. Group A receives Physical activity. Group B receives no study treatment and is followed for comparison.

One site, in Québec

2 groups
One site, in Québec
Recruiting

Official title: Physical Activity Program for Reducing Blood Pressure in Sleep Apnea Patients With Resistant Hypertension

Hypertension, Resistant to Conventional Therapy · AGIR à Dom

Testing Measurement of pulmonary functional for pulmonary hypertension

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Everyone in this study is in one group and receives Measurement of pulmonary functional capillary surface area.

One site, in Montreal

1 group
One site, in Montreal
Recruiting

Official title: Functional Pulmonary Capillary Surface Area in BPA for CTEPH

Hypertension, Pulmonary · Jewish General Hospital

Comparing 4 approaches for glaucoma and ocular hypertension

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There are 4 groups in this study. Groups A and C, the comparison group, receive Standard Energy SLT. Groups B and D receive Low Energy SLT.

One site, in Kitchener

Phase 3
4 groups
One site, in Kitchener
Recruiting

Official title: Clarifying the Optimal Application of SLT Therapy Trial

Glaucoma and Ocular Hypertension · University of Pittsburgh

Comparing Stretching exercise with Walking exercise for hypertension

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There are 2 groups in this study. Group A receives Stretching exercise. Group B receives Walking exercise.

One site, in Saskatoon

2 groups
One site, in Saskatoon
Recruiting

Official title: Stretching vs Walking for Lowering Blood Pressure

Hypertension · University of Saskatchewan

Testing Reference Treatment against a placebo for hypertension in type 2 diabetes

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There are 3 groups in this study. Group A, the comparison group, receives Active Treatment. Group B, the comparison group, receives Reference Treatment. Group C, the placebo group, receives Control.

One site, in Toronto

3 groups
One site, in Toronto
Recruiting

Official title: The SWITCH (Substitution of High With Low Ultra-processed Soy Protein Foods In a Guideline-based Diet inTervention for Cardiometabolic Health) Trial

Hypertension in Type 2 Diabetes · University of Toronto

Testing IKT-001 against a placebo for pulmonary arterial hypertension

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There are 2 groups in this study. Group A receives IKT-001. Group B, the placebo group, receives Placebo.

One site, in Edmonton

Phase 3
2 groups
One site, in Edmonton
Recruiting

Official title: An Adaptive Program of IKT-001 in Pulmonary Arterial Hypertension (PAH)

Pulmonary Arterial Hypertension · Inhibikase Therapeutics

Comparing Hyperpolarized (13) Pyruvate with Gadolinium for hypertension

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There are 2 groups in this study. Group A receives Hyperpolarized (13) Pyruvate Injection. Group B receives one or more of: Hyperpolarized (13) Pyruvate Injection and Gadolinium.

2 sites in Toronto

Phase 1
2 groups
2 sites in Toronto
Recruiting

Official title: Metabolic Imaging of the Heart Using Hyperpolarized (13C) Pyruvate Injection

Hypertension · Sunnybrook Health Sciences Centre

Comparing 4 approaches for hypertension

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There are 4 groups in this study. Groups A, B, C and D, the comparison group, receive awake ABPM.

One site, in Montreal

4 groups
One site, in Montreal
Recruiting

Official title: Accuracy Testing of Validated and Non-validated Home BP Devices Sold on the Online Market.

Hypertension · Centre Integre Universitaire de Sante et Services Sociaux du Nord de l'ile de Montreal

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Concord provides information support only. Trial listings come from public registries; eligibility is always determined by the trial site and your care team.