Double-blind
Neither you nor the study team knows which group you are in.
What it means
In a double-blind study, both the participant and the study staff working with them are kept unaware of which treatment that participant is receiving until the study ends.
Why it matters if you take part
Knowing which treatment someone received can influence how they report how they feel, and how staff record results. Blinding removes that influence.
What it looks like in practice
The registry lists masking as DOUBLE, TRIPLE, or QUADRUPLE depending on how many groups of people are kept unaware. There is always a way to unblind urgently if a doctor needs to know for safety.
Related terms
Trials recruiting now that are double-blind
302 recruiting trials in our Canadian corpus are double-blind.
A Safety and Tolerability Study of HJB647 in Heart Failure Participants With Reduced Ejection Fraction
Heart Failure With Reduced Ejection Fraction · PHASE1
Study to Evaluate Efficacy and Safety of ONL1204 in Patients With GA Associated With AMD
Geographic Atrophy (GA) · PHASE2
Virtual Reality for Pain and Well-Being in Older Adults
Chronic Pain · NA
A Clinical Study of Islatravir and Ulonivirine for People With HIV-1 Who Have Not Been Treated Before (MK-8591B-062)
Human Immunodeficiency Virus Type 1 (HIV-1) Infection · PHASE2
RCT of Mind-body in Long COVID and Myalgic Encephalomyelitis
Myalgic Encephalomyelitis/Chronic Fatigue Syndrome · NA
LY4268989 (MORF-057) Co-Administered With Mirikizumab in Adults With Moderately to Severely Active Ulcerative Colitis:
Ulcerative Colitis · PHASE2
This explains how clinical research works. It is not medical advice and does not describe any specific condition or treatment. Only a trial site can determine whether someone can take part in a study.