Melanoma Clinical Trials

19 trials recruiting in Canada.

Cancer

Recruiting Drug Device Behavioral Older adults Healthy volunteers

14 trials

Testing Darovasertib with Crizotinib (Xalkori) for uveal melanoma

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One site, in Toronto

Official title: Study of Adjuvant Darovasertib and Crizotinib in Participants With Primary Non-metastatic Uveal Melanoma

Uveal Melanoma · IDEAYA Biosciences

Comparing Darovasertib with Primary Local Therapy for uveal melanoma

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Sites in Edmonton and Toronto

RecruitingPHASE3

Official title: Neoadjuvant Darovasertib in Primary Uveal Melanoma

Uveal Melanoma · IDEAYA Biosciences

Comparing Stereotactic Body Radiotherapy with Immunotherapy alone for melanoma metastatic

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One site, in Toronto

RecruitingPHASE2

Official title: Stereotactic Ablative Radiotherapy (XRT) and Immunotherapy for Oligometastatic Extracranial Melanoma

Melanoma Metastatic · Melanoma Institute Australia

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Comparing IMA203 with nivolumab plus relatlimab for cutaneous malignant melanoma

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Sites in Edmonton, Montreal and 2 more cities

RecruitingPHASE3

Official title: SUPRAME-ACTengine® IMA203 vs. Investigator's Choice of Treatment in Previously Treated, Unresectable or Metastatic Cutaneous Melanoma

Melanoma, Cutaneous Malignant · Immatics US, Inc.

Comparing 3 approaches for advanced melanoma

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One site, in Toronto

RecruitingPHASE2

Official title: Safety and Efficacy of EIK1001 in Combo With Pembro Versus Placebo and Pembro as First-Line Therapy in Patients With Advanced Melanoma.

Advanced Melanoma · Eikon Therapeutics

Testing LND101 for melanoma

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Sites in Montreal, Toronto and 10 more cities

RecruitingPHASE2

Official title: LND101 for Fecal Microbiota Transplantation in Combination With Immune Checkpoint Blockade in Advanced Melanoma

Melanoma · Canadian Cancer Trials Group

Comparing Opdualag with Nivolumab for cutaneous melanoma

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One site, in Toronto

RecruitingPHASE2

Official title: Clear Me: Interception Trial to Detect and Clear Molecular Residual Disease in Patients With High-risk Melanoma

Cutaneous Melanoma · University Health Network, Toronto

Comparing fianlimab with relatlimab+nivolumab for melanoma

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Sites in Toronto, Edmonton and 3 more cities

RecruitingPHASE3

Official title: A Study With Combinations of Anti-LAG-3 and Anti-PD-1 Antibodies in Adult Participants With Advanced or Metastatic Melanoma (Harmony Head-to-Head)

Melanoma · Regeneron Pharmaceuticals

Comparing 3 approaches for advanced melanoma

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Sites in Edmonton and Toronto

RecruitingPHASE3

Official title: IMC-F106C Regimen Versus Nivolumab Regimens in Previously Untreated Advanced Melanoma (PRISM-MEL-301)

Advanced Melanoma · Immunocore Ltd

Testing Nicotinamide against a placebo for non-melanoma skin cancer

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Sites in Toronto, Vancouver and 3 more cities

RecruitingPHASE3

Official title: Nicotinamide Chemoprevention for Keratinocyte Carcinoma in Solid Organ Transplant Recipients - Pivotal Trial

Non-melanoma Skin Cancer · Women's College Hospital

Testing Definity with Sonalleve Focused Ultrasound Device for melanoma

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One site, in Toronto

RecruitingPHASE1

Official title: MRI-Guided Focused Ultrasound Radiosensitization for Patients With Malignant Melanoma and Non Melanoma Skin Cancer

Melanoma · Sunnybrook Health Sciences Centre

Comparing 3 approaches for advanced melanoma

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Sites in Montreal, Toronto and 1 more city

RecruitingPHASE3

Official title: Tebentafusp Regimen Versus Investigator's Choice in Previously Treated Advanced Melanoma (TEBE-AM)

Advanced Melanoma · Immunocore Ltd

Comparing Intermittent PD-1 inhibitor therapy with Continuous PD-1 inhibitor therapy for unresectable/metastatic melanoma

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Sites in Toronto, Barrie and 16 more cities

RecruitingPHASE3

Official title: Duration of Anti-PD-1 Therapy in Metastatic Melanoma

Unresectable/Metastatic Melanoma · Canadian Cancer Trials Group

Comparing 8 approaches for metastatic uveal melanoma

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One site, in Toronto

RecruitingPHASE1

Official title: Study of IDE196 in Patients With Solid Tumors Harboring GNAQ/11 Mutations or PRKC Fusions

Metastatic Uveal Melanoma · IDEAYA Biosciences

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Concord provides information support only. Trial listings come from public registries; eligibility is always determined by the trial site and your care team.