Ovarian Cancer Clinical Trials

21 trials recruiting in Canada.

Cancer

Recruiting Drug Device Behavioral Older adults Healthy volunteers

21 trials

Comparing Bilateral Salpingectomy with Bilateral Salpingectomy with for ovarian carcinoma

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Sites in Montreal and Vancouver

Official title: A Study to Compare Two Surgical Procedures in Individuals With BRCA1 Mutations to Assess Reduced Risk of Ovarian Cancer

Ovarian Carcinoma · NRG Oncology

Comparing INCB123667 with Investigator's choice of chemotherapy for ovarian cancer

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Sites in Montreal, Calgary and 3 more cities

RecruitingPHASE3

Official title: Study to Evaluate INCB123667 Versus Investigator's Choice of Chemotherapy in Participants With Platinum-Resistant Ovarian Cancer With Cyclin E1 Overexpression

Ovarian Cancer · Incyte Corporation

Testing Niraparib for ovarian neoplasms

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Sites in Kelowna, Montreal and 1 more city

RecruitingPHASE2

Official title: A Long-term Treatment Extension Study of Niraparib in Participants Who Completed a Prior GlaxoSmithKline/TESARO-sponsored Niraparib Study

Ovarian Neoplasms · GlaxoSmithKline

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Comparing 6 approaches for ovarian cancer

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Sites in Montreal, Edmonton and 2 more cities

RecruitingPHASE1

Official title: Phase I/IIa Study of AZD5335 as Monotherapy and Combination Therapy in Participants With Solid Tumors

Ovarian Cancer · AstraZeneca

Testing BMS-986463 for high-grade serous ovarian carcinoma (HGSOC)

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Sites in Montreal, Toronto and 1 more city

RecruitingPHASE1

Official title: A Study to Evaluate the Safety, Tolerability, and Efficacy of Escalating Doses of BMS-986463 in Participants With Select Advanced Malignant Tumors.

High-grade Serous Ovarian Carcinoma (HGSOC) · Bristol-Myers Squibb

Comparing 3 approaches for ovarian cancer

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Sites in Montreal, Calgary and 3 more cities

RecruitingPHASE3

Official title: A Study to Evaluate the Efficacy and Safety of Sacituzumab Tirumotecan (MK-2870) Maintenance Treatment Versus Standard of Care in Participants With Platinum-sensitive Recurrent Ovarian Cancer (MK-2870-022/TroFuse-022/ENGOT-ov84/GOG-3103)

Ovarian Cancer · Merck Sharp & Dohme LLC

Comparing Minimally Invasive Surgery with Laparotomy for advanced ovarian carcinoma

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Sites in Calgary and Toronto

RecruitingPHASE3

Official title: Minimally Invasive Surgery After Neoadjuvant Chemotherapy for the Treatment of Stage IIIC-IV Ovarian, Primary Peritoneal, or Fallopian Tube Cancer, LANCE Trial

Advanced Ovarian Carcinoma · M.D. Anderson Cancer Center

Comparing 4 approaches for epithelial ovarian cancer

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Sites in Montreal, Edmonton and 3 more cities

RecruitingPHASE3

Official title: AZD5335 vs. Mirvetuximab Soravtansine in FRα-high and AZD5335 vs. Chemotherapy in FRα-low Platinum-resistant Ovarian Cancer

Epithelial Ovarian Cancer · AstraZeneca

Comparing 6 approaches for ovarian neoplasms

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Sites in Toronto, Calgary and 4 more cities

RecruitingPHASE3

Official title: A Three-Part Phase 3 Study of Sofetabart Mipitecan in Participants With Platinum-Resistant (Part A) and Platinum-Sensitive (Parts B and C) Ovarian Cancer

Ovarian Neoplasms · Eli Lilly and Company

Comparing Sacituzumab tirumotecan with Bevacizumab for ovarian neoplasms

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Sites in Montreal and Chicoutimi

RecruitingPHASE3

Official title: A Clinical Trial of Sac-TMT in People With Non-HRD Positive Advanced Ovarian Cancer (MK-2870-021)

Ovarian Neoplasms · Merck Sharp & Dohme LLC

Comparing 14 approaches for ovarian cancer recurrent

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2 sites in Montreal

RecruitingPHASE1

Official title: A Clinical Study of Raludotatug Deruxtecan in People With Ovarian Cancer (MK-5909-003)

Ovarian Cancer Recurrent · Merck Sharp & Dohme LLC

Comparing 3 approaches for ovarian cancer

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Sites in Toronto, Kelowna and 2 more cities

RecruitingPHASE2

Official title: Immunotherapy Platform Study in Platinum Resistant High Grade Serous Ovarian Cancer

Ovarian Cancer · Canadian Cancer Trials Group

Comparing 3 approaches for epithelial ovarian cancer

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Sites in Montreal, Toronto and 2 more cities

RecruitingPHASE2

Official title: CATALINA-2: A Clinical Study of TORL-1-23 in Platinum-resistant Ovarian Cancer.

Epithelial Ovarian Cancer · TORL Biotherapeutics, LLC

Testing Estetrol/Drospirenone for ovarian endometrioma

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One site, in Montreal

RecruitingPHASE4

Official title: Estetrol/Drospirenone to Reduce the Average Size of Endometriomas

Ovarian Endometrioma · Andrew Zakhari

Comparing Mocertatug rezetecan with Paclitaxel for ovarian neoplasms

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2 sites in Montreal

RecruitingPHASE3

Official title: A Study to Investigate Mocertatug Rezetecan Compared With Standard of Care in Participants With Platinum-resistant Ovarian Cancer (BEHOLD-Ovarian01)

Ovarian Neoplasms · GlaxoSmithKline

Testing Niraparib for ovarian cancer

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One site, in Toronto

RecruitingPHASE2

Official title: Alternative Dosing Of Niraparib To Decrease Dose Interruption In First Line Maintenance Treatment For Ovarian Cancer

Ovarian Cancer · Sunnybrook Health Sciences Centre

Comparing 6 approaches for ovarian cancer

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Sites in Montreal, Greenfield Park and 3 more cities

RecruitingPHASE2

Official title: Investigation of Ubamatamab Combination Therapy in Adult Participants With Platinum-Resistant Ovarian Cancer

Ovarian Cancer · Regeneron Pharmaceuticals

Testing Patients that are HRP are given a for ovarian cancer

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One site, in Saskatoon

Recruiting

Official title: Patient Preferences for Precision Medicine: Determining Optimal Patient Quality of Life Using PARPi's

Ovarian Cancer · University of Saskatchewan

Comparing 4 approaches for platinum-resistant ovarian cancer

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Sites in Montreal and Toronto

RecruitingPHASE2

Official title: A Study of Lorigerlimab in Participants With Advanced Solid Tumors

Platinum-resistant Ovarian Cancer · MacroGenics

Comparing Azenosertib with Investigator's choice of Chemotherapy for ovarian cancer

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Sites in Montreal, Sherbrooke and 1 more city

RecruitingPHASE3

Official title: A Study of Azenosertib (ZN-c3) Versus Investigator's Choice Chemotherapy in Subjects With Platinum-Resistant High-Grade Serous Ovarian, Primary Peritoneal, or Fallopian Tube Cancers Positive for Cyclin E1 Protein Expression

Ovarian Cancer · K-Group, Beta, Inc., a wholly owned subsidiary of Zentalis Pharmaceuticals, Inc

Comparing avutometinib with Pegylated liposomal doxorubicin for low grade serous ovarian cancer

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Sites in Montreal, Toronto and 1 more city

RecruitingPHASE3

Official title: A Study of Avutometinib (VS-6766) + Defactinib (VS-6063) in Recurrent Low-Grade Serous Ovarian Cancer

Low Grade Serous Ovarian Cancer · Verastem, Inc.

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Concord provides information support only. Trial listings come from public registries; eligibility is always determined by the trial site and your care team.