Pancreatic Cancer Clinical Trials

Official title: A Phase 2 Study of VS-7375 in Patients With KRAS G12D-Mutated Pancreatic Cancer

Pancreatic Ductal Adenocarcinoma (PDAC) · Verastem, Inc.

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Comparing Cobimetinib with Ponatinib for pancreatic ductal carcinoma

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One site, in Toronto

Official title: Using Tumor Models to Determine Treatments

Pancreatic Ductal Carcinoma · University Health Network, Toronto

Testing Diffusing Alpha Radiation Emitters for pancreatic cancer

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One site, in Montreal

Official title: Alpha Radiation Emitters (DaRT) With Chemotherapy for the Treatment of Locally Advanced and Metastatic Pancreatic Cancer

Pancreatic Cancer · Alpha Tau Medical LTD.

Testing High dose radiation therapy for locally advanced pancreatic adenocarcinoma

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Sites in Montreal and Toronto

Official title: A Study of High Dose Radiation Therapy for Locally Advanced Pancreatic Cancer That Responded to Initial Chemotherapy Treatment

Locally Advanced Pancreatic Adenocarcinoma · University Health Network, Toronto

Testing Pancreatic resection and non-anatomic for pancreas adenocarcinoma

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One site, in Québec

Official title: Pancreatic Cancer and Synchronous Liver Metastases Resection Following Neoadjuvant FOLFIRINOX

Pancreas Adenocarcinoma · Laval University

Testing Biospecimen Collection with Computed Tomography for metastatic pancreatic neuroendocrine tumor

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One site, in Toronto

Official title: Testing the Addition of Sunitinib Malate to Lutetium Lu 177 Dotatate (Lutathera) in Pancreatic Neuroendocrine Tumors

Metastatic Pancreatic Neuroendocrine Tumor · National Cancer Institute (NCI)

Testing enoxaparin/tinzaparin/dalteparin for pancreas cancer

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One site, in Toronto

RecruitingPHASE4

Official title: Pre- Vs. Postoperative Thromboprophylaxis in Pancreatic Surgery

Pancreas Cancer · Helsinki University Central Hospital

Comparing Endocrinologist-directed target blood with Standard Care for pancreatic cancer

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Sites in Toronto and Vancouver

Official title: Monitoring and Managing Glucose Levels in People With Pancreatic Cancer

Pancreatic Cancer · British Columbia Cancer Agency

Testing Irreversible electroporation for locally advanced pancreatic cancer

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Sites in Regina and Saskatoon

Official title: Systemic Therapy With a Loco-regional Treatment in Patients With Locally Advanced Pancreatic Cancer

Locally Advanced Pancreatic Cancer · University of Saskatchewan

Comparing 3 approaches for pancreatic ductal adenocarcinoma

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One site, in Vancouver

Official title: Using Tumour DNA and Proteins to Better Understand How Pancreatic Cancer Responds to Treatment

Pancreatic Ductal Adenocarcinoma · British Columbia Cancer Agency

Comparing 3 approaches for pancreatic cancer

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One site, in Edmonton

Official title: Durvalumab and Tremelimumab in Combination With Propranolol and Chemotherapy for Treatment of Advanced Hepatopancreabiliary Tumors (BLOCKED)

Pancreatic Cancer · AHS Cancer Control Alberta

Comparing EUS-CPN with bupivacaine with EUS-CPN without bupivacaine for pancreatic cancer

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One site, in Montreal

Official title: EUS-CPN With and Without Bupivacaine

Pancreatic Cancer · Centre hospitalier de l'Université de Montréal (CHUM)

Comparing 3 approaches for pancreatic ductal adenocarcinoma

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Sites in Ottawa and Toronto

Official title: MOONRAY-01, A Study of LY3962673 in Participants With KRAS G12D-Mutant Solid Tumors

Pancreatic Ductal Adenocarcinoma · Eli Lilly and Company

Testing [68Ga]Ga-NNS309 with [177Lu]Lu-NNS309 for pancreatic ductal adenocarcinoma

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Sites in Montreal and Toronto

Official title: Phase I Study of [177Lu]Lu-NNS309 in Patients With Pancreatic, Lung, Breast and Colorectal Cancers

Pancreatic Ductal Adenocarcinoma · Novartis Pharmaceuticals

Testing 68Ga-NNS309 with 177Lu-DFC413 for pancreatic ductal adenocarcinoma

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One site, in Montreal

Official title: Phase I Study of [177Lu]Lu-DFC413 in Patients With Solid Tumors

Pancreatic Ductal Adenocarcinoma · Novartis Pharmaceuticals

Testing WEF-001 for advanced or metastatic KRAS-mutant tumor in pancreatic

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One site, in Toronto

Official title: Phase 1/2a Study to Assess the Safety, Tolerability, Pharmacokinetics, and Preliminary Efficacy of WEF-001 as Monotherapy in Advanced KRAS-Mutant Solid Tumours.

Advanced or Metastatic KRAS-mutant Tumor in Pancreatic Adenocarcinoma · Auricula Biosciences Inc.

Testing mFOLFIRINOX with Gemcitabine / Nab-paclitaxel for pancreatic adenocarcinoma

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One site, in Hamilton

Official title: Pancreatic Adenocarcinoma Neoadjuvant Chemotherapy Before Surgery

Pancreatic Adenocarcinoma · Hamilton Health Sciences Corporation

Testing Durvalumab with Oleclumab for pancreatic ductal adenocarcinoma

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One site, in Toronto

Official title: Durvalumab and Oleclumab in Resectable PDAC

Pancreatic Ductal Adenocarcinoma · University Health Network, Toronto

Comparing Autogene cevumeran with mFOLFIRINOX for pancreatic ductal adenocarcinoma

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Sites in Montreal and Toronto

Official title: A Study of the Efficacy and Safety of Adjuvant Autogene Cevumeran Plus Atezolizumab and mFOLFIRINOX Versus mFOLFIRINOX Alone in Participants With Resected PDAC

Adenocarcinoma, Pancreatic Ductal · Genentech, Inc.

Testing Fecal Microbiota Transplantation with PEG3350 for unresectable or metastatic advanced pancreatic ductal

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One site, in London