Type 1 Diabetes Clinical Trials

20 trials recruiting in Canada.

Diabetes & Hormones

Recruiting Drug Device Behavioral Older adults Healthy volunteers

20 trials

Testing Semaglutide against a placebo for type 1 diabetes

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There are 2 groups in this study. Group A receives Semaglutide. Group B, the placebo group, receives Placebo.

One site, in Montreal

Phase 2
2 groups
One site, in Montreal
Recruiting

Official title: Lean Mass Changes With Semaglutide in Adults With Type 1 Diabetes and Overweight/Obesity.

Type 1 Diabetes · McGill University Health Centre/Research Institute of the McGill University Health Centre

Testing Teplizumab against a placebo for type 1 diabetes mellitus

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There are 2 groups in this study. Group A receives Teplizumab. Group B, the placebo group, receives Placebo.

Sites in Calgary, Halifax and 2 more cities

Phase 3
2 groups
Sites in Calgary, Vancouver and 2 more cities
Recruiting

Official title: A Study to Investigate Efficacy and Safety of Teplizumab Compared With Placebo in Participants 1 to 25 Years of Age With Stage 3 Type 1 Diabetes

Type 1 Diabetes Mellitus · Sanofi

Comparing 3 approaches for type 1 diabetes mellitus

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There are 3 groups in this study. Groups A, B and C receive VV-14300.

One site, in Toronto

Phase 1
3 groups
One site, in Toronto
Recruiting

Official title: VV-14300 for the Treatment of Type 1 Diabetes

Type 1 Diabetes Mellitus · Kriya Therapeutics, Inc.

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Testing Rezpegaldesleukin against a placebo for type 1 diabetes mellitus

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There are 2 groups in this study. Group A receives Rezpegaldesleukin. Group B, the placebo group, receives Placebo.

One site, in Vancouver

Phase 2
2 groups
One site, in Vancouver
Recruiting

Official title: Rezpegaldesleukin (NKTR-358) in New Onset Type 1 Diabetes Mellitus

Type 1 Diabetes Mellitus · National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Testing DPP System (Insulin Pump and Continuous for type 1 diabetes mellitus

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Everyone in this study is in one group and receives DPP System (Insulin Pump and Continuous Glucose Monitoring Platform).

One site, in Toronto

Early Phase 1
1 group
One site, in Toronto
Recruiting

Official title: Simultaneous Measurement and Responsive Treatment - Part 2

Type 1 Diabetes Mellitus · ClinSurge Research

Comparing Tirzepatide with Carbohydrate Counting for type 1 diabetes

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There are 2 groups in this study. Group A receives Tirzepatide, together with one or more of: Tandem Control-IQ Automated Insulin Delivery System (with Dexcom G7 CGM), Carbohydrate Counting and No Meal Announcement. Group B, the comparison group, receives one or more of: Tandem Control-IQ Automated Insulin Delivery System (with Dexcom G7 CGM) and Carbohydrate Counting.

3 sites in Montreal

Phase 2
2 groups
3 sites in Montreal
Recruiting

Official title: A Clinical Trial Using Tirzepatide to Help Adults With Type 1 Diabetes Automatically Control Their Blood Sugar

Type 1 Diabetes · McGill University Health Centre/Research Institute of the McGill University Health Centre

Testing Biological/Vaccine for type 1 diabetes

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Everyone in this study is in one group and receives Biological/Vaccine.

Sites in Toronto and Vancouver

Phase 3
1 group
Sites in Toronto and Vancouver
Recruiting

Official title: An Efficacy, Safety, and Tolerability Study of VX-880 in Participants With Type 1 Diabetes With a Kidney Transplant

Type 1 Diabetes · Vertex Pharmaceuticals Incorporated

Comparing TECC-T1D3 Program with Education Intervention for type 1 diabetes (T1D)

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There are 2 groups in this study. Group A receives TECC-T1D3 Program. Group B, the comparison group, receives Education Intervention.

One site, in Toronto

2 groups
One site, in Toronto
Recruiting

Official title: Technology-Enabled Collaborative Care for Young Adults With Type 1 Diabetes and Diabetes Distress: A Feasibility Trial

Type 1 Diabetes (T1D) · Centre for Addiction and Mental Health

Testing Missed Dose with Missed Dose + 15min walk (MISS+EX) for type 1 diabetes mellitus

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Everyone in this study is in one group, which receives one or more of: Control (CON), Missed Dose (MISS) and Missed Dose + 15min walk (MISS+EX).

One site, in Montreal

1 group
One site, in Montreal
Recruiting

Official title: Physical Activity to Prevent and Treat Hyperglycemia From a Mistimed Bolus Insulin Dose

Type 1 Diabetes Mellitus · Jane Yardley

Comparing 3 approaches for type 1 diabetes mellitus

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There are 3 groups in this study. Groups A, B and C, the comparison group, receive one or more of: MTX228 and DEXCOM G6.

One site, in Edmonton

Phase 2
3 groups
One site, in Edmonton
Recruiting

Official title: An Adaptive Design Study of MTX228

Type 1 Diabetes Mellitus · University of Alberta

Testing 12-week TEAM peer mentor program for type 1 diabetes

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There are 2 groups in this study. Group A receives 12-week TEAM peer mentor program. Group B receives no study treatment and is followed for comparison.

Sites in Mississauga and Winnipeg

2 groups
Sites in Winnipeg and Mississauga
Recruiting

Official title: Type 1 Diabetes, Exercise and Mentoring Trial

Type 1 Diabetes · University of Manitoba

Testing High repetition (HI) with Moderate repetition for type 1 diabetes

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Everyone in this study is in one group, which receives one or more of: High repetition (HI) and Moderate repetition (MOD).

One site, in Edmonton

1 group
One site, in Edmonton
Recruiting

Official title: Effects of Resistance Exercise on Blood Glucose in Post-menopausal Women With Type 1 Diabetes

Type 1 Diabetes · University of Alberta

Testing Aerobic Exercise with Resistance Exercise for type 1 diabetes

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Everyone in this study is in one group, which receives one or more of: Aerobic Exercise, Resistance Exercise and No exercise.

Sites in Edmonton and Montreal

1 group
Sites in Edmonton and Montreal
Recruiting

Official title: Aerobic vs Resistance Exercise in Post-menopausal Women With Type 1 Diabetes

Type 1 Diabetes · University of Alberta

Testing Prebiotic against a placebo for type 1 diabetes

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There are 2 groups in this study. Group A receives Prebiotic. Group B, the placebo group, receives Placebo.

Sites in Calgary, Edmonton and 1 more city

2 groups
Sites in Calgary, Edmonton and 1 more city
Recruiting

Official title: Prebiotics in Patients With Type 1 Diabetes

Type 1 Diabetes · University of Calgary

Testing Oral Carbohydrate (CHO) Administration against a placebo for type 1 diabetes

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There are 3 groups in this study. Group A, the placebo group, receives Oral Carbohydrate (CHO) Administration for Hypoglycemia Prevention and Treatment. Groups B and C receive Oral Carbohydrate (CHO) Administration for Hypoglycemia Prevention and Treatment.

2 sites in Montreal

3 groups
2 sites in Montreal
Recruiting

Official title: Updating Preventive and Treatment Guidelines for Hypoglycemia in Individuals Living With Type 1 Diabetes

Type 1 Diabetes · Institut de Recherches Cliniques de Montreal

Testing Semaglutide with 4 meal strategies for type 1 diabetes

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There are 2 groups in this study. Group A, the comparison group, receives Placebo with 4 meal strategies. Group B receives Semaglutide with 4 meal strategies.

One site, in Montreal

Phase 2
2 groups
One site, in Montreal
Recruiting

Official title: Alleviating Carbohydrate Counting for Patients with Type-1 Diabetes Using a Closed Loop System with Weekly Subcutaneous Semaglutide

Type 1 Diabetes · McGill University Health Centre/Research Institute of the McGill University Health Centre

Comparing 3 approaches for type 1 diabetes mellitus with hypoglycemia

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There are 3 groups in this study. Group A receives one or more of: Placebo and ZT-01, 7 mg. Group B receives one or more of: Placebo and ZT-01, 15 mg. Group C receives one or more of: Placebo and ZT-01, 22 mg.

Sites in Calgary, Toronto and 4 more cities

Phase 2
3 groups
Sites in Calgary, Vancouver and 4 more cities
Recruiting

Official title: A Study of the Effect of ZT-01 on Night-time Hypoglycemia in Type 1 Diabetes

Type 1 Diabetes Mellitus With Hypoglycemia · Zucara Therapeutics Inc.

Testing Peer support meetings for type 1 diabetes (T1D)

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Everyone in this study is in one group and receives Peer support meetings.

One site, in Québec

1 group
One site, in Québec
Recruiting

Official title: CommuniT1D: A Customized Virtual Peer Support Program For People Living With Type 1 Diabetes In Canada

Type 1 Diabetes (T1D) · Laval University

Testing Luteal Phase Aerobic Exercise with Follicular Phase Aerobic Exercise for type 1 diabetes

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Everyone in this study is in one group, which receives one or more of: Luteal Phase Aerobic Exercise and Follicular Phase Aerobic Exercise.

One site, in Edmonton

1 group
One site, in Edmonton
Recruiting

Official title: Exercise and the Menstrual Cycle in Type 1 Diabetes

Type 1 Diabetes · University of Alberta

Testing Support platform for type 1 diabetes

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There are 2 groups in this study. Group A receives Support platform. Group B, the comparison group, receives Support platform.

Sites in Montreal, Québec and 1 more city

2 groups
Sites in Montreal, Québec and 1 more city
Recruiting

Official title: Implementation of Support in the Care of Adults Living With Type 1 Diabetes

Type 1 Diabetes · McGill University

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Concord provides information support only. Trial listings come from public registries; eligibility is always determined by the trial site and your care team.