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2,972 Canadian clinical trials, in plain language.

Recruiting Drug Device Behavioral Older adults Healthy volunteers

10 trials matching “Major Depressive Disorder”

Comparing Treatment As Usual with CARIBOU-2 for major depressive disorder

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There are 2 groups in this study. Group A, the comparison group, receives Treatment As Usual. Group B receives CARIBOU-2.

One site, in Toronto

2 groups
One site, in Toronto
Recruiting

Official title: Effectiveness of an Integrated Care Pathway for Depression: Cluster Randomized Controlled Trial

Major Depressive Disorder · Centre for Addiction and Mental Health

Testing Escitalopram against a placebo for major depressive disorder

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There are 4 groups in this study. Groups A and C, the comparison group, receive Escitalopram and Brexpiprazole. Groups B and D, the placebo group, receive Escitalopram.

Sites in Toronto, Calgary and 7 more cities

Phase 4
4 groups
Sites in Calgary, Vancouver and 7 more cities
Recruiting

Official title: Optimized Predictive Treatment In Medications for Unipolar Major Depression (OPTIMUM-D)

Major Depressive Disorder · Nova Scotia Health Authority

Testing Building Regulation in Dual Generations for maternal depression

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There are 2 groups in this study. Group A receives Building Regulation in Dual Generations (BRIDGE; DBT + Parenting). Group B receives no study treatment and is followed for comparison.

Sites in Montreal and Winnipeg

2 groups
Sites in Winnipeg and Montreal
Recruiting

Official title: Enhancing Preschool Children's Attention and Behaviour: Parent-Focused Program

Maternal Depression · McGill University

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Testing bWell Cognitive Remediation with VR Experience against a placebo for major depressive disorder

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There are 2 groups in this study. Group A, the comparison group, receives bWell Cognitive Remediation. Group B, the sham group, receives VR Experience.

One site, in Vancouver

2 groups
One site, in Vancouver
Recruiting

Official title: bWell-D Pilot Randomized Controlled Trial

Depressive Disorder, Major · University of British Columbia

Testing Brexpiprazole for bipolar depression

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Everyone in this study is in one group and receives Brexpiprazole.

Sites in Montreal and Hamilton

Phase 3
1 group
Sites in Hamilton and Montreal
Recruiting

Official title: Brexpiprazole Treatment for Bipolar I Depression

Bipolar Depression · Douglas Mental Health University Institute

Testing The Building Emotional Awareness and for anxiety depression

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Everyone in this study is in one group and receives The Building Emotional Awareness and Mental Health (BEAM) Program.

One site, in Winnipeg

1 group
One site, in Winnipeg
Recruiting

Official title: Building Emotional Awareness and Mental Health (BEAM) 2024-2027

Depression, Anxiety · Leslie E. Roos

Comparing 4 approaches for depression

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There are 4 groups in this study. Group A receives Tunneled Delivery and Standard Resources, together with one or more of: Transdiagnostic Self-Guided ICBT. Group B receives Tunneled Delivery and Enhanced Social Learning Resources, together with one or more of: Transdiagnostic Self-Guided ICBT. Group C receives Personalized Delivery and Standard Resources, together with one or more of: Transdiagnostic Self-Guided ICBT. …and 1 more groups.

One site, in Regina

4 groups
One site, in Regina
Recruiting

Official title: Assessing Social Learning and Course Delivery Timing in Internet-delivered Cognitive Behaviour Therapy for Public Safety Personnel

Depression · University of Regina

Testing Attachment and Child Health (ATTACH) for depression

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Everyone in this study is in one group and receives Attachment and Child Health (ATTACH) Parenting Program.

One site, in Calgary

1 group
One site, in Calgary
Recruiting

Official title: Adaptation and Pilot Testing of Web and Mobile Interface for the ATTACH™ Intervention

Depression · University of Calgary

Comparing Repetitive Transcranial Magnetic with Research Interview, Questionnaires for major depressive disorder

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There are 2 groups in this study. Group A receives one or more of: Repetitive Transcranial Magnetic Stimulation, Research Interview, Questionnaires, Brain Scan and Saliva Samples. Group B receives one or more of: Research Interview, Questionnaires, Brain Scan and Saliva Samples.

One site, in Toronto

2 groups
One site, in Toronto
Recruiting

Official title: The Impact of Working Memory and Reward Markers on DLPFC Activity in Treatment-resistant Depression

Major Depressive Disorder · Unity Health Toronto

Comparing Traditional Country Foods with Cultural Workshops for anxiety depression

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There are 2 groups in this study. Groups A and B receive one or more of: Traditional Country Foods and Cultural Workshops.

2 sites in Arviat

Early Phase 1
2 groups
2 sites in Arviat
Recruiting

Official title: Integrating Inuit Knowledge Principles in Multi-Level Mental Health Clinical Trials

Depression, Anxiety · University of Alberta

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Concord provides information support only. Trial listings come from public registries; eligibility is always determined by the trial site and your care team.