Crohn's Disease Clinical Trials

Trials for someone you care about with crohn's disease.

Digestive Health

Recruiting Drug Device Behavioral Older adults Healthy volunteers

30 trials

Testing IV Tulisokibart against a placebo for Crohn's disease

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Sites in London, Montreal and 13 more cities

Official title: A Study to Evaluate the Efficacy and Safety of Tulisokibart (MK-7240) in Participants With Moderate to Severe Crohn's Disease (MK-7240-008)

Crohn's Disease · Merck Sharp & Dohme LLC

Comparing 3 approaches for Crohn's disease

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Sites in Edmonton, London and 5 more cities

RecruitingPHASE4

Official title: A Study of Vedolizumab Intravenous (IV) and Adalimumab or Vedolizumab and Ustekinumab in Adults With Crohn's Disease

Crohn's Disease · Takeda

Comparing Mirikizumab - with LY4395089 for crohn disease

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Sites in Lethbridge, London and 1 more city

RecruitingPHASE2

Official title: A Study of LY4395089 and Mirikizumab (LY3074828) Given Together and Mirikizumab (Alone) in Adults With Crohn's Disease

Crohn Disease · Eli Lilly and Company

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Comparing Guselkumab with Risankizumab for crohn disease

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Sites in Montreal, Edmonton and 5 more cities

RecruitingPHASE3

Official title: A Study of Guselkumab Versus Risankizumab in Participants With Moderately to Severely Active Crohn's Disease

Crohn Disease · Janssen Research & Development, LLC

Testing IFX + mCDED for crohn disease (CD)

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One site, in Vancouver

Recruiting

Official title: Combining Nutritional Therapy and Anti-TNFα Treatment in Pediatric Patients With Crohn's Disease

Crohn Disease (CD) · University of British Columbia

Testing Ustekinumab for crohn disease (CD)

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One site, in Montreal

RecruitingPHASE4

Official title: De-escalation of Ustekinumab Therapy in Patients With Crohn's Disease and Ulcerative Colitis

Crohn Disease (CD) · McGill University Health Centre/Research Institute of the McGill University Health Centre

Testing Duvakitug against a placebo for Crohn's disease

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Sites in Hamilton and Toronto

RecruitingPHASE3

Official title: A Maintenance Study to Investigate the Efficacy and Safety of Duvakitug in Participants With Moderately to Severely Active Crohn's Disease

Crohn's Disease · Sanofi

Testing Duvakitug against a placebo for Crohn's disease

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Sites in Brampton, Edmonton and 5 more cities

RecruitingPHASE3

Official title: An Induction Study to Investigate the Efficacy and Safety of Duvakitug in Participants With Moderately to Severely Active Crohn's Disease

Crohn's Disease · Sanofi

Testing Mirikizumab for crohn disease

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Sites in London, Scarborough Village and 1 more city

RecruitingPHASE4

Official title: Open-label Single-arm Study to Assess the Efficacy of Mirikizumab in Patients With Inflammatory Strictures Due to CD

Crohn Disease · Alimentiv Inc.

Testing Afimkibart against a placebo for moderately to severely active crohns disease

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Sites in London, Barrie and 3 more cities

RecruitingPHASE3

Official title: A Study to Assess the Efficacy and Safety of Induction Therapy With Afimkibart (RO7790121) in Participants With Moderately to Severely Active Crohn's Disease

Moderately to Severely Active Crohns Disease · Hoffmann-La Roche

Testing Afimkibart against a placebo for moderately to severely active crohns disease

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Sites in Edmonton, Trois-Rivières and 1 more city

RecruitingPHASE3

Official title: A Study to Assess the Efficacy and Safety of Induction and Maintenance Therapy With Afimkibart (RO7790121) in Participants With Moderately to Severely Active Crohn's Disease

Moderately to Severely Active Crohns Disease · Hoffmann-La Roche

Testing SAR441566 against a placebo for Crohn's disease

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Sites in Calgary, Montreal and 1 more city

RecruitingPHASE2

Official title: A Study to Investigate Efficacy and Safety of SAR441566 in Patients With Crohn's Disease.

Crohn's Disease · Sanofi

Comparing 7 approaches for Crohn's disease

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Sites in Edmonton, Calgary and 5 more cities

RecruitingPHASE2

Official title: Study of Targeted Therapies for the Treatment of Adult Participants With Moderate to Severe Crohn's Disease

Crohn's Disease · AbbVie

Comparing 6 approaches for Crohn's disease

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Sites in Halifax, Montreal and 1 more city

RecruitingPHASE3

Official title: Crohn's Disease: Efficacy, Safety, and Pharmacokinetics of Upadacitinib in Pediatric Subjects With Moderately to Severely Active Crohn's Disease

Crohn's Disease · AbbVie

Comparing KleanLyte with Bi-PegLyte for crohn disease

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One site, in Winnipeg

RecruitingPHASE4

Official title: Bowel Preparation for Colonoscopy Among Individuals With Crohn's and Ulcerative Colitis Disease.

Crohn Disease · University of Manitoba

Testing Vedolizumab for moderately to severely active Crohn's disease

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Sites in London, Bridgewater and 3 more cities

RecruitingPHASE4

Official title: VECTORS - A Study to Evaluate Transmural Healing as a Treatment Target in Crohn's Disease

Moderately to Severely Active Crohn's Disease · Alimentiv Inc.

Comparing 4 approaches for Crohn's disease

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Sites in London, Montreal and 4 more cities

RecruitingPHASE2

Official title: A Study on the Safety of TAK-279 and Whether it Can Reduce Inflammation in the Bowel of Participants With Moderately to Severely Active Crohn's Disease

Crohn's Disease · Takeda

Testing Vedolizumab against a placebo for Crohn's disease

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Sites in Barrie, Calgary and 7 more cities

RecruitingPHASE3

Official title: A Study of Vedolizumab With and Without Upadacitinib in Adults With Crohn's Disease

Crohn's Disease · Takeda

Comparing Whole-food based smoothie with Formula for crohn disease

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One site, in Halifax

Recruiting

Official title: Reverse-Engineering of Exclusive Enteral Nutrition (RE-EEN) in Crohn's Disease: A Multi-Center Trial

Crohn Disease · Seattle Children's Hospital

Comparing 3 approaches for crohn disease

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Sites in Montreal, Toronto and 14 more cities

RecruitingPHASE4

Official title: PATHFINDER: Evaluating the Optimal First-Line Treatment Strategy for Moderate-to-Severely Active Ileal-dominant Crohn's Disease

Crohn Disease · University of Calgary

Testing Anti-TNF therapy for crohn disease

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Sites in Edmonton, London and 2 more cities

RecruitingPHASE4

Official title: Clinical, Imaging, and Endoscopic Outcomes of Children Newly Diagnosed With Crohn's Disease

Crohn Disease · Connecticut Children's Medical Center

Comparing 9 approaches for Crohn's disease (CD)

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Sites in Edmonton, London and 2 more cities

RecruitingPHASE3

Official title: A Study of Vedolizumab in Children and Teenagers With Moderate to Severe Crohn's Disease (CD)

Crohn's Disease (CD) · Takeda

Testing Dietary Intakes (Reference protein for crohn disease

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One site, in Toronto

Recruiting

Official title: Threonine Requirement in Adult Males With Crohn's Disease Using IAAO

Crohn Disease · The Hospital for Sick Children

Comparing 15 approaches for Crohn's disease

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Sites in Calgary, Edmonton and 2 more cities

RecruitingPHASE3

Official title: A Study to Assess Adverse Events, Change in Disease Activity, and How Intravenous and Subcutaneous Risankizumab Moves Through the Body of Pediatric Participants With Moderately to Severely Active Crohn's Disease

Crohn's Disease · AbbVie

Comparing Tirzepatide with Mirikizumab for Crohn's disease

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Sites in London, Vancouver and 3 more cities

RecruitingPHASE3

Official title: Mirikizumab and Tirzepatide Administered in Adult Participants With Moderately to Severely Active Crohn's Disease and Obesity or Overweight

Crohn's Disease · Eli Lilly and Company

Comparing 3 approaches for Crohn's disease

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Sites in Halifax, London and 2 more cities

RecruitingPHASE3

Official title: A Study of Mirikizumab (LY3074828) in Pediatric Participants With Crohn's Disease

Crohn's Disease · Eli Lilly and Company

Comparing 5 approaches for Crohn's disease

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Sites in Halifax, London and 1 more city

RecruitingPHASE3

Official title: A Study of Guselkumab in Pediatric Participants With Moderately to Severely Active Crohn's Disease

Crohn's Disease · Janssen Research & Development, LLC

TIDHI Mental Health in IBD Patients Study

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One site, in North York

Recruiting

Crohn Disease (CD) · TIDHI Innovation Inc.

Comparing JNJ-78934804 with Guselkumab for crohn disease

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Sites in Edmonton, Montreal and 5 more cities

RecruitingPHASE3

Official title: A Study of JNJ-78934804 in Participants With Moderately to Severely Active Crohn's Disease

Crohn Disease · Janssen Research & Development, LLC

Testing Icotrokinra against a placebo for crohn disease

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Sites in Barrie, Edmonton and 6 more cities

RecruitingPHASE2

Official title: A Study of Icotrokinra in Participants With Moderately to Severely Active Crohn's Disease

Crohn Disease · Janssen Research & Development, LLC

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Concord provides information support only. Trial listings come from public registries; eligibility is always determined by the trial site and your care team.