Leukemia Clinical Trials

Trials for someone you care about with leukemia.

Cancer

Recruiting Drug Device Behavioral Older adults Healthy volunteers

50 trials · showing 30

Comparing Biospecimen Collection with Bone Marrow Aspiration for chronic lymphocytic leukemia

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Sites in Halifax, Montreal and 6 more cities

Official title: Testing Early Treatment for Patients With High-Risk Chronic Lymphocytic Leukemia (CLL) or Small Lymphocytic Leukemia (SLL), EVOLVE CLL/SLL Study

Chronic Lymphocytic Leukemia · National Cancer Institute (NCI)

Testing Elritercept against a placebo for myelodysplastic syndromes

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Sites in Toronto, Edmonton and 3 more cities

RecruitingPHASE3

Official title: A Study of Elritercept to Treat Anemia in Adults With Very Low, Low, or Intermediate Risk Myelodysplastic Syndromes (MDS) Who Need Regular Blood Transfusions

Myelodysplastic Syndromes · Takeda

Comparing 4 approaches for acute lymphoblastic leukaemia

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Sites in Calgary, Montral and 4 more cities

RecruitingPHASE2

Official title: Allogeneic Stem Cell Transplantation for Children and Adolescents With Acute Lymphoblastic Leukaemia

Acute Lymphoblastic Leukaemia · St. Anna Kinderkrebsforschung

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Comparing Nemtabrutinib with Rituximab for leukemia, lymphocytic, chronic, b-cell

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Sites in Greenfield Park, Moncton and 1 more city

RecruitingPHASE3

Official title: A Study of Nemtabrutinib Plus Venetoclax vs Venetoclax + Rituximab (VR) in Second-line (2L) + Relapsed/Refractory (R/R) Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma (CLL/SLL) (MK-1026-010/BELLWAVE-010).

Leukemia, Lymphocytic, Chronic, B-Cell · Merck Sharp & Dohme LLC

Testing EASE-psy for acute leukemia

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Sites in Toronto, Hamilton and 2 more cities

Recruiting

Official title: Emotion and Symptom-Focused Engagement Trial for Individuals With Acute Leukemia

Acute Leukemia · Canadian Cancer Trials Group

Comparing Allopurinol with Doxorubicin for b acute lymphoblastic leukemia

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Sites in Calgary, Halifax and 3 more cities

RecruitingPHASE3

Official title: Inotuzumab Ozogamicin and Frontline Chemotherapy in Treating Young Adults With Newly Diagnosed B Acute Lymphoblastic Leukemia

B Acute Lymphoblastic Leukemia · Alliance for Clinical Trials in Oncology

Comparing 11 approaches for chronic myelogenous leukemia

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One site, in Montreal

RecruitingPHASE4

Official title: Asciminib Roll-over Study

Chronic Myelogenous Leukemia · Novartis Pharmaceuticals

Comparing 3 approaches for chronic lymphocytic leukemia

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Sites in Montreal, Québec and 1 more city

RecruitingPHASE3

Official title: A Study of Pirtobrutinib (LOXO-305) Versus Ibrutinib in Participants With Chronic Lymphocytic Leukemia (CLL)/Small Lymphocytic Lymphoma (SLL)

Chronic Lymphocytic Leukemia · Loxo Oncology, Inc.

Testing Dexamethasone with Mitoxantrone for lymphoblastic leukemia

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Sites in Montreal, Calgary and 4 more cities

RecruitingPHASE1

Official title: TINI 2: Total Therapy for Infants With Acute Lymphoblastic Leukemia II

Lymphoblastic Leukemia · Tanja Andrea Gruber

Testing Tranexamic acid against a placebo for myelodysplastic syndromes

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One site, in Winnipeg

RecruitingPHASE2

Official title: Evaluation of Tranexamic Acid in Myelodysplastic Syndromes and Acute Myeloid Leukemia

Myelodysplastic Syndromes · University of Manitoba

Testing Ziftomenib against a placebo for acute myeloid leukemia (AML)

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One site, in Montreal

RecruitingPHASE3

Official title: Studies to Assess Ziftomenib in Combination With Ven+Aza or 7+3 in Patients With Untreated NPM1-m or KMT2A-r AML

Acute Myeloid Leukemia (AML) · Kura Oncology, Inc.

Testing Ibrutinib for chronic lymphocytic leukemia

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One site, in Montreal

RecruitingPHASE3

Official title: A Long-term Extension Study of PCI-32765 (Ibrutinib)

Chronic Lymphocytic Leukemia · Janssen Research & Development, LLC

Comparing 14 approaches for leukemia, myeloid, acute

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Sites in Calgary and Edmonton

RecruitingPHASE1

Official title: A Phase 1/2 Study of Enzomenib (DSP-5336) in Patients With Acute Leukemia (Horizen-1)

Leukemia, Myeloid, Acute · Sumitomo Pharma America, Inc.

Testing CLIC-2201 for b-cell leukemia

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Sites in Calgary, Toronto and 2 more cities

RecruitingPHASE1

Official title: CLIC-2201 for the Treatment of Relapsed/Refractory B Cell Malignancies

B-Cell Leukemia · British Columbia Cancer Agency

Comparing 3 approaches for acute myeloid leukemia

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Sites in Montreal, Calgary and 6 more cities

RecruitingPHASE2

Official title: Comparing Cytarabine + Daunorubicin Therapy Versus Cytarabine + Daunorubicin + Venetoclax Versus Venetoclax + Azacitidine in Younger Patients With Intermediate Risk AML (A MyeloMATCH Treatment Trial)

Acute Myeloid Leukemia · National Cancer Institute (NCI)

Comparing 4 approaches for chronic lymphocytic leukemia

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Sites in Barrie and Saskatoon

RecruitingPHASE2

Official title: A Study Evaluating the Efficacy and Safety of Pirtobrutinib in Participants With Relapsed or Refractory Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma

Chronic Lymphocytic Leukemia · Loxo Oncology, Inc.

Comparing Nemtabrutinib with Ibrutinib for chronic lymphocytic leukemia

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Sites in Brampton, Kelowna and 4 more cities

RecruitingPHASE3

Official title: A Study of Nemtabrutinib (MK-1026) Versus Comparator (Investigator's Choice of Ibrutinib or Acalabrutinib) in First Line (1L) Chronic Lymphocytic Leukemia (CLL)/ Small Lymphocytic Lymphoma (SLL) (MK-1026-011/BELLWAVE-011)

Chronic Lymphocytic Leukemia · Merck Sharp & Dohme LLC

Testing RBC transfusion strategy for acute leukemia

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One site, in Hamilton

Recruiting

Official title: Biomarkers in Patients With Anemia-Induced Thrombocytopenic Bleeding

Acute Leukemia · Donald Arnold

Testing AZD4512 monotherapy for b-cell acute lymphoblastic leukemia (b-ALL)

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Sites in Toronto and Vancouver

RecruitingPHASE1

Official title: Study of AZD4512 Monotherapy or in Combination With Anticancer Agents in Participants With Acute Lymphoblastic Leukemia

B-cell Acute Lymphoblastic Leukemia (B-ALL) · AstraZeneca

Comparing 6 approaches for myelodysplastic syndromes

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Sites in St. John's and Toronto

RecruitingPHASE2

Official title: A Multi-phase Study of ASTX030 (Azacitidine and Cedazuridine) in Myeloid Neoplasm Alone or in Combination With Venetoclax in AML (AZTOUND Study)

Myelodysplastic Syndromes · Taiho Oncology, Inc.

Testing CLIC-1901 for acute lymphoblastic leukemia

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Sites in Ottawa, Vancouver and 1 more city

RecruitingPHASE1

Official title: CLIC-1901 for the Treatment of Patients With Relapsed/Refractory CD19 Positive Hematologic Malignancies

Acute Lymphoblastic Leukemia · Ottawa Hospital Research Institute

Testing Luspatercept for myelodysplastic syndromes (MDS)

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3 sites in Toronto

RecruitingPHASE3

Official title: A Study to Evaluate Long-term Safety in Participants Who Have Participated in Other Luspatercept (ACE-536) Clinical Trials

Myelodysplastic Syndromes (MDS) · Celgene

Testing Bleximenib for acute leukemia

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Sites in Montreal, Toronto and 1 more city

RecruitingPHASE1

Official title: A Phase 1/2 Study of Bleximenib in Participants With Acute Leukemia (cAMeLot-1)

Acute Leukemia · Janssen Research & Development, LLC

Testing RBC transfusion for myelodysplastic syndrome

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One site, in Hamilton

Recruiting

Official title: Revisiting the Universal Donor: Does Exposure to O Blood Products Affect Patient Outcomes?

Myelodysplastic Syndrome · McMaster University

Testing Bleximenib with Venetoclax against a placebo for leukemia, myeloid, acute

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Sites in Calgary, Halifax and 6 more cities

RecruitingPHASE3

Official title: A Study of Bleximenib, Venetoclax and Azacitidine For Treatment of Participants With Newly Diagnosed Acute Myeloid Leukemia (AML)

Leukemia, Myeloid, Acute · Janssen Research & Development, LLC

Testing revumenib with cobicistat for acute myeloid leukemia

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2 sites in Toronto

RecruitingPHASE1

Official title: A Study of Revumenib in R/R Leukemias Including Those With an MLL/KMT2A Gene Rearrangement or NPM1 Mutation

Acute Myeloid Leukemia · Syndax Pharmaceuticals

Testing Zilovertamab vedotin for b-cell acute lymphoblastic leukemia

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Sites in Calgary, Montreal and 1 more city

RecruitingPHASE1

Official title: Substudy 01A: Zilovertamab Vedotin in Pediatric and Young Adult Participants With Hematologic Malignancies or Solid Tumors (MK-9999-01A/LIGHTBEAM-U01)

B-cell Acute Lymphoblastic Leukemia · Merck Sharp & Dohme LLC

Comparing Pirtobrutinib with Idelalisib for chronic lymphocytic leukemia

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One site, in Toronto

RecruitingPHASE4

Official title: A Study of Pirtobrutinib (LY3527727) in Participants With Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma

Chronic Lymphocytic Leukemia · Eli Lilly and Company

Comparing Fludarabine with Venetoclax for acute myeloid leukemia

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Sites in Calgary, Halifax and 4 more cities

RecruitingPHASE3

Official title: Venetoclax in Children With Relapsed Acute Myeloid Leukemia (AML)

Acute Myeloid Leukemia · PedAL BCU, LLC

Comparing 7 approaches for acute lymphoblastic leukaemia

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Sites in Montreal and Toronto

RecruitingPHASE1

Official title: Study of AZD3632 Monotherapy or in Combination With Anticancer Agents in Participants With Advanced Haematologic Malignancies With KMT2Ar, NPM1m, or Other Genotypes Associated With HOX Overexpression

Acute Lymphoblastic Leukaemia · AstraZeneca

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Concord provides information support only. Trial listings come from public registries; eligibility is always determined by the trial site and your care team.