Major Depressive Disorder Clinical Trials

65 trials recruiting in Canada.

Mental Health

Recruiting Drug Device Behavioral Older adults Healthy volunteers

21 trials

Comparing Things You Do Program (Ultra-Brief ICBT) with Things You Do Program (Ultra-Brief ICBT for depression

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One site, in Regina

Recruiting

Official title: An Ultra-Brief ICBT Intervention: The 'Things You Do' Program

Depression · University of Regina

Comparing Eating ad libitum with nutritional with Time restricted eating for bipolar depression

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One site, in Ottawa

Recruiting

Official title: SYNCED - SYNChronized Eating in Bipolar Depression Study

Bipolar Depression · University of Ottawa

Comparing 4 approaches for perinatal depression

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One site, in Toronto

RecruitingPHASE2

Official title: Perinatal Depression & Anxiety (PDA) and Maternal Gut Microbiome

Perinatal Depression · The Canadian College of Naturopathic Medicine

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Testing PSP Wellbeing Course for anxiety depression

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One site, in Regina

Recruiting

Official title: Internet-Delivered Cognitive Behaviour Therapy for Public Safety Personnel

Depression, Anxiety · University of Regina

Testing dialectical behavior therapy for depression - major depressive disorder

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One site, in Windsor

Recruiting

Official title: Feasibility and Acceptability of an E-learning Dialectical Behavior Therapy Skills Course

Depression - Major Depressive Disorder · University of Windsor

Testing Building Regulation in Dual Generations for maternal depression

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Sites in Montreal and Winnipeg

Recruiting

Official title: Enhancing Preschool Children's Attention and Behaviour: Parent-Focused Program

Maternal Depression · McGill University

Testing Acceptance and Commitment Therapy with Ketamine for depression - major depressive disorder

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One site, in Montreal

Recruiting

Official title: ACT_for Alcohol Use Disorder and Depression

Depression - Major Depressive Disorder · Centre hospitalier de l'Université de Montréal (CHUM)

Testing bWell Cognitive Remediation with VR Experience against a placebo for major depressive disorder

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One site, in Vancouver

Recruiting

Official title: bWell-D Pilot Randomized Controlled Trial

Depressive Disorder, Major · University of British Columbia

Comparing Ketamine hydrochloride with Midazolam Hydrochloride for major depressive disorder

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One site, in Toronto

RecruitingPHASE2

Official title: i-CBT and IV Ketamine for Suicidality in Treatment-Resistant Depression: A Randomized, Midazolam-Controlled Clinical Trial

Major Depressive Disorder · University Health Network, Toronto

Comparing e-CBT with e-CBT + Phone Call for depression

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One site, in Kingston

Recruiting

Official title: Comparing Clinical Decision-making of AI Technology to a Multi-professional Care Team in ECBT for Depression

Depression · Dr. Nazanin Alavi

Comparing 3 approaches for depression

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One site, in Regina

Recruiting

Official title: Internet-delivered Cognitive Behaviour Therapy for Students: Duration Preference Trial

Depression · University of Regina

Comparing Cognitive-Behavioural Therapy with Antidepressant medication for depression

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Sites in Halifax and Montreal

RecruitingPHASE2

Official title: Treatment Interrupts Depression Early

Depression · Nova Scotia Health Authority

Comparing Cognitive Behavioral Therapy with Pharmacotherapy for major depressive disorder

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One site, in Halifax

RecruitingPHASE4

Official title: Personalized Indications for CBT and Antidepressants in Treating Depression

Major Depressive Disorder · Nova Scotia Health Authority

Testing The Building Emotional Awareness and for anxiety depression

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One site, in Winnipeg

Recruiting

Official title: Building Emotional Awareness and Mental Health (BEAM) 2024-2027

Depression, Anxiety · Leslie E. Roos

Comparing 4 approaches for depression

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One site, in Regina

Recruiting

Official title: Assessing Social Learning and Course Delivery Timing in Internet-delivered Cognitive Behaviour Therapy for Public Safety Personnel

Depression · University of Regina

Comparing Psilocybin with Microcrystalline cellulose for depressive disorder

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One site, in Toronto

RecruitingPHASE2

Official title: A Randomized Neuroimaging Trial of Psilocybin in Depression

Depressive Disorder · Sunnybrook Health Sciences Centre

Testing PA program - MoveU.HappyU for treatment-resistant depression

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One site, in Toronto

Recruiting

Official title: Physical Activity Program for TRD

Treatment-resistant Depression · Unity Health Toronto

Testing Attachment and Child Health (ATTACH) for depression

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One site, in Calgary

Recruiting

Official title: Adaptation and Pilot Testing of Web and Mobile Interface for the ATTACH™ Intervention

Depression · University of Calgary

Comparing ADAPT Treatment with Incredible Years Parenting Program for depression / major depressive disorder

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One site, in Toronto

Recruiting

Official title: Optimizing Treatment for Depressed Parents of Children With Emotional and Behavioural Problems

Depression / Major Depressive Disorder · University of Toronto

Comparing Repetitive Transcranial Magnetic with Research Interview, Questionnaires for major depressive disorder

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One site, in Toronto

Recruiting

Official title: The Impact of Working Memory and Reward Markers on DLPFC Activity in Treatment-resistant Depression

Major Depressive Disorder · Unity Health Toronto

Comparing Traditional Country Foods with Cultural Workshops for anxiety depression

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2 sites in Arviat

RecruitingEARLY PHASE1

Official title: Integrating Inuit Knowledge Principles in Multi-Level Mental Health Clinical Trials

Depression, Anxiety · University of Alberta

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Concord provides information support only. Trial listings come from public registries; eligibility is always determined by the trial site and your care team.