Major Depressive Disorder Clinical Trials

65 trials recruiting in Canada.

Mental Health

Recruiting Drug Device Behavioral Older adults Healthy volunteers

25 trials

Testing Transcranial Magnetic Stimulation for major depressive diorder

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Sites in North York and Toronto

RecruitingPHASE1

Official title: qEEG Brain Signature of Depression & Neuromodulation-induced Recovery

Major Depressive Diorder · Sunnybrook Health Sciences Centre

Testing Theta Burst Stimulation for depression

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One site, in Ottawa

Recruiting

Official title: Comparing the Efficacy of Accelerated vs. Standard fMRI-guided iTBS in Treating Adolescents Depression

Depression · The Royal Ottawa Mental Health Centre

Testing iTBS Stimulation against a placebo for bipolar depression

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2 sites in Toronto

Recruiting

Official title: Theta-Burst Stimulation for Bipolar Depression

Bipolar Depression · Centre for Addiction and Mental Health

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Testing active tDCS with workbook against a placebo for major depression

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2 sites in Toronto

Recruiting

Official title: RCT of At-Home tDCS for Depression in Pregnancy

Major Depression · Women's College Hospital

Comparing Intermittent Theta Burst Stimulation with Low Frequency Right for depression

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Sites in Toronto and Vancouver

Recruiting

Official title: Left vs. Right Non-Inferiority Trial

Depression · University of British Columbia

Comparing 3 approaches for major depressive episode

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One site, in Ottawa

Recruiting

Official title: Comparing Uni- and Bi-lateral TBS in Major Depression

Major Depressive Episode · The Royal Ottawa Mental Health Centre

Testing Brainsway H1-Coil Deep TMS System for major depressive disorder

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One site, in Toronto

Recruiting

Official title: Deep TMS for Comorbid Depression and Cognitive Impairment in Older Adults

Major Depressive Disorder · Rotman Research Institute at Baycrest

Testing Active Brainsway H7-Coil Deep TMS System against a placebo for major depressive disorder (MDD)

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One site, in Toronto

Recruiting

Official title: Accelerated Neuromodulation of Anterior Cingulate Cortex for Depression

Major Depressive Disorder (MDD) · Rotman Research Institute at Baycrest

Testing repetitive transcranial magnetic for major depression moderate

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One site, in Toronto

Recruiting

Official title: rTMS for Youth Inpatients With Depression

Major Depression Moderate · Sunnybrook Health Sciences Centre

Testing ExAblate Neuro 4000 for treatment-resistant depression

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One site, in Toronto

Recruiting

Official title: Magnetic Resonance-Guided Focused Ultrasound Bilateral Capsulotomy for the Treatment of Refractory Bipolar Depression

Treatment-Resistant Depression · Sunnybrook Health Sciences Centre

Comparing Spaced iTBS with Compressed iTBS for major depressive disorder (MDD)

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One site, in Toronto

RecruitingPHASE1

Official title: Theta-Burst Stimulation to Treat Depression

Major Depressive Disorder (MDD) · Centre for Addiction and Mental Health

Testing MagPro X100/R30 stimulator, Cool-B70 for bipolar depression depressed phase

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2 sites in Toronto

RecruitingPHASE3

Official title: Low Frequency Right Dorsolateral Pre Frontal Cortical Repetitive TMS for Bipolar Depression

Bipolar Depression Depressed Phase · Tyler Kaster

Testing repetitive Transcranial Magnetic for depression

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One site, in Ottawa

Recruiting

Official title: Comparing the Efficacy of fMRI-Guided vs. Standard iTBS in Treating Depression

Depression · The Royal Ottawa Mental Health Centre

Testing Temporal Interference stimulation against a placebo for major depressive disorder

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One site, in Toronto

Recruiting

Official title: Temporal Interference and Depression

Major Depressive Disorder · Unity Health Toronto

Testing TBS for late life depression (LLD)

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2 sites in Toronto

Recruiting

Official title: Accelerated vs. Conventional Theta Burst Stimulation for Late-life Depression

Late Life Depression (LLD) · Centre for Addiction and Mental Health

Comparing Oculus VR headset with Ketamine for treatment resistant depression

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One site, in Toronto

RecruitingPHASE3

Official title: InTRavenous kEtAmine and immerSive virtUal Reality to Treat dEpression

Treatment Resistant Depression · Sunnybrook Health Sciences Centre

Testing iTBS for major depressive disorder

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2 sites in Toronto

Recruiting

Official title: E-field Guided iTBS for Treatment Resistant Depression

Major Depressive Disorder · Centre for Addiction and Mental Health

Testing Repetitive Transcranial Magnetic for treatment-resistant depressive disorder

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Sites in Edmonton and Halifax

Recruiting

Official title: rTMS With and Without Text4Support for the Treatment of Resistant Depression.

Depressive Disorder, Treatment-Resistant · University of Alberta

Testing EXOMIND (BTL-699-2) Active Treatment with EMSELLA (HPM-6000UF) ActiveTreatment against a placebo for depressive symptoms

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One site, in Toronto

Recruiting

Official title: BTL-699-2 and HPM-6000UF Devices for the Improvement of Depressive Symptoms and Sexual Function Among Perimenopausal and Postmenopausal Women

Depressive Symptoms · BTL Industries Ltd.

Comparing Negative ion therapy with Light therapy for major depressive disorder, recurrent, in remission

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One site, in Vancouver

Recruiting

Official title: Light and Ion Maintenance In Treatment for Depression (LIMIT-D): Feasibility Study

Major Depressive Disorder, Recurrent, in Remission · University of British Columbia

Testing Next Generation Dome Helmet for treatment-resistant depression

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One site, in Toronto

Recruiting

Official title: Focused Ultrasound Neuromodulation in Patients With Treatment-Resistant Depression

Treatment-Resistant Depression · Sunnybrook Health Sciences Centre

Testing tDCS with Treatment as Usual against a placebo for major depressive disorder (MDD)

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One site, in Montreal

Recruiting

Official title: Home-Based tDCS for Depression in BPD

Major Depressive Disorder (MDD) · Ciusss de L'Est de l'Île de Montréal

Testing Theta burst stimulation for major depressive disorder (MDD)

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One site, in Ottawa

Recruiting

Official title: Feasibility Trial of Exercise as a Priming Strategy for rTMS Treatment in Difficult-to-Treat Depression

Major Depressive Disorder (MDD) · The Royal Ottawa Mental Health Centre

Comparing Repetitive Transcranial Magnetic with Research Interview, Questionnaires for major depressive disorder

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One site, in Toronto

Recruiting

Official title: The Impact of Working Memory and Reward Markers on DLPFC Activity in Treatment-resistant Depression

Major Depressive Disorder · Unity Health Toronto

Testing rTMS for major depressive disorder

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One site, in Toronto

Recruiting

Official title: Interleaved TMS-fMRI in Ultra-treatment Resistant Depression

Major Depressive Disorder · Sunnybrook Health Sciences Centre

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Concord provides information support only. Trial listings come from public registries; eligibility is always determined by the trial site and your care team.