Rheumatoid Arthritis Clinical Trials

Trials for someone you care about with rheumatoid arthritis.

Arthritis & Autoimmune

Recruiting Drug Device Behavioral Older adults Healthy volunteers

21 trials

Testing Eloralintide against a placebo for osteoarthritis

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There are 4 groups in this study. Groups A and C receive Eloralintide. Groups B and D, the placebo group, receive Placebo.

Sites in Québec, Toronto and 3 more cities

Phase 3
4 groups
Sites in Guelph, Québec and 3 more cities
Recruiting

Official title: Efficacy and Safety of Eloralintide (LY3841136) in Participants With Osteoarthritis Knee Pain and Obesity or Overweight

Osteoarthritis · Eli Lilly and Company

Testing Hydroxychloroquine against a placebo for arthritis

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There are 2 groups in this study. Group A receives Hydroxychloroquine. Group B, the placebo group, receives Placebo.

One site, in Edmonton

Phase 2
2 groups
One site, in Edmonton
Recruiting

Official title: Immune-Mediated Pathophysiology And Clinical Triage Program

Arthritis · AHS Cancer Control Alberta

Testing Tulisokibart against a placebo for radiographic axial spondyloarthritis

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There are 4 groups in this study. Groups A, B and C receive Tulisokibart. Group D, the placebo group, receives Placebo.

Sites in Québec, Toronto and 1 more city

Phase 2
4 groups
Sites in Toronto, Québec and 1 more city
Recruiting

Official title: A Clinical Study of Tulisokibart (MK-7240) to Treat Radiographic Axial Spondyloarthritis (MK-7240-013)

Radiographic Axial Spondyloarthritis · Merck Sharp & Dohme LLC

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Testing AZD1163 against a placebo for rheumatoid arthritis

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There are 4 groups in this study. Groups A, B and C receive AZD1163. Group D, the placebo group, receives Placebo.

Sites in Niagara Falls, Ottawa and 2 more cities

Phase 2
4 groups
Sites in Niagara Falls, Ottawa and 2 more cities
Recruiting

Official title: A Study to Investigate Efficacy and Safety of AZD1163 in Participants With Rheumatoid Arthritis

Rheumatoid Arthritis · AstraZeneca

Testing Lutikizumab against a placebo for rheumatoid arthritis

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There are 6 groups in this study. Group A receives Lutikizumab. Groups B, D and F, the placebo group, receive Placebo. Group C receives Ravagalimab. …and 1 more groups.

Sites in Calgary, Saskatoon and 1 more city

Phase 2
6 groups
Sites in Calgary, Sherbrooke and 1 more city
Recruiting

Official title: A Study to Evaluate Different Targeted Therapies for Patients With Rheumatoid Arthritis

Rheumatoid Arthritis · AbbVie

Testing Icotrokinra against a placebo for psoriatic arthritis

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There are 3 groups in this study. Groups A and B receive Icotrokinra. Group C, the placebo group, receives Placebo, together with one or more of: Icotrokinra.

Sites in Montreal, Orillia and 5 more cities

Phase 3
3 groups
Sites in St. John's, Orillia and 5 more cities
Recruiting

Official title: A Study to Evaluate the Efficacy and Safety of Icotrokinra (JNJ-77242113) in Biologic-experienced and Biologic-naive Participants With Active Psoriatic Arthritis

Arthritis, Psoriatic · Janssen Research & Development, LLC

Comparing targeted synthetic DMARD class with non-TNFi-biologic class for rheumatoid arthritis

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There are 2 groups in this study. Group A, the comparison group, receives targeted synthetic DMARD class. Group B, the comparison group, receives non-TNFi-biologic class.

One site, in Toronto

Phase 3
2 groups
One site, in Toronto
Recruiting

Official title: RA-PRO PRAGMATIC TRIAL

Rheumatoid Arthritis · University of Alabama at Birmingham

Testing Orforglipron against a placebo for osteoarthritis

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There are 4 groups in this study. Groups A and C receive Orforglipron. Groups B and D, the placebo group, receive Placebo.

Sites in Québec, Brampton and 4 more cities

Phase 3
4 groups
Sites in Brampton, Joliette and 4 more cities
Recruiting

Official title: A Study of Orforglipron (LY3502970) in Participants With Obesity or Overweight and Osteoarthritis (OA) of the Knee

Osteoarthritis · Eli Lilly and Company

Testing Tulisokibart against a placebo for psoriatic arthritis

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There are 4 groups in this study. Groups A, B and C receive Tulisokibart. Group D, the placebo group, receives Placebo.

Sites in Rimouski and Trois-Rivières

Phase 2
4 groups
Sites in Rimouski and Trois-Rivières
Recruiting

Official title: Study to Evaluate Tulisokibart in Adults With Psoriatic Arthritis (MK-7240-015)

Psoriatic Arthritis · Merck Sharp & Dohme LLC

Testing Sonelokimab against a placebo for psoriatic arthritis

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There are 4 groups in this study. Groups A and B receive Sonelokimab. Group C, the placebo group, receives Placebo. Group D, the comparison group, receives Risankizumab.

Sites in Calgary, Toronto and 3 more cities

Phase 3
4 groups
Sites in Toronto, Calgary and 3 more cities
Recruiting

Official title: Evaluation of Sonelokimab in Patients With Active Psoriatic Arthritis and Anti-TNFα Inadequate Response

Arthritis, Psoriatic · MoonLake Immunotherapeutics AG

Comparing 3 approaches for psoriatic arthritis

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There are 3 groups in this study. Groups A and B receive Zasocitinib. Group C receives Placebo, together with one or more of: Zasocitinib.

Sites in Niagara Falls, Québec and 1 more city

Phase 3
3 groups
Sites in Niagara Falls, Toronto and 1 more city
Recruiting

Official title: A Study of Zasocitinib in Adults With Psoriatic Arthritis Who Have or Have Not Been Treated With Biologic Medicines

Psoriatic Arthritis · Takeda

Testing Glucocorticoid (GC) for rheumatoid arthritis (RA)

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There are 2 groups in this study. Groups A and B receive Glucocorticoid (GC).

5 sites in Toronto

Phase 4
2 groups
5 sites in Toronto
Recruiting

Official title: Oral Versus Intramuscular Steroid Use to Control Rheumatoid Arthritis Flares

Rheumatoid Arthritis (RA) · Sunnybrook Health Sciences Centre

Comparing 3 approaches for psoriatic arthritis

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There are 3 groups in this study. Group A receives Risankizumab. Group B receives Lutikizumab. Group C receives Lutikizumab and Risankizumab.

Sites in Saskatoon and Trois-Rivières

Phase 2
3 groups
Sites in Trois-Rivières and Saskatoon
Recruiting

Official title: Study of Targeted Therapies for the Treatment of Adult Participants With Active Psoriatic Arthritis

Psoriatic Arthritis · AbbVie

Testing Upadacitinib against a placebo for psoriatic arthritis

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There are 2 groups in this study. Group A receives Upadacitinib 15 MG [Rinvoq]. Group B, the placebo group, receives Placebo.

Sites in Ottawa and Québec

Phase 4
2 groups
Sites in Ottawa and Québec
Recruiting

Official title: A Study to Evaluate the Impact of Upadacitinib on Spondyloarthritis Outcomes in Patients With Active Psoriatic Arthritis

Psoriatic Arthritis · CARE ARTHRITIS LTD.

Comparing 4 approaches for rheumatoid arthritis

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There are 4 groups in this study. Group A, the comparison group, receives TNFi. Groups B and C, the comparison group, receive Anti-IL6. Group D, the comparison group, receives JAKi.

One site, in Montreal

4 groups
One site, in Montreal
Recruiting

Official title: Stand UP to Rheumatoid Arthritis (SUPRA)

Rheumatoid Arthritis · Marie Hudson, MD

Comparing Etanercept with tofacitinib for rheumatoid arthritis

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There are 2 groups in this study. Group A, the comparison group, receives Etanercept. Group B, the comparison group, receives tofacitinib.

One site, in London

Phase 4
2 groups
One site, in London
Recruiting

Official title: Advanced Therapeutics in Rheumatoid Arthritis (RA)

Rheumatoid Arthritis · London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's

Testing Duloxetine against a placebo for knee osteoarthritis

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There are 2 groups in this study. Group A receives Duloxetine. Group B, the placebo group, receives Placebo.

2 sites in Toronto

Phase 4
2 groups
2 sites in Toronto
Recruiting

Official title: Effect of peRiopErative duLoxetIne Administration on Opioid Consumption Following Total kneE Arthroplasty (RELIFE)

Knee Osteoarthritis · Sunnybrook Health Sciences Centre

Testing Triamcinolone Acetonide for trapeziometacarpal osteoarthritis

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There are 2 groups in this study. Group A receives Saline Solution (NaCl 0,9%). Group B, the comparison group, receives Triamcinolone Acetonide.

2 sites in Montreal

Phase 2
2 groups
2 sites in Montreal
Recruiting

Official title: Corticosteroid Against Saline Injections for Thumb Osteoarthritis (CASITOA)

Trapeziometacarpal Osteoarthritis · Université du Québec à Trois-Rivières

Testing Multiprofen-CC™ plus standard treatment against a placebo for hand osteoarthritis

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There are 2 groups in this study. Group A receives Multiprofen-CC™ plus standard treatment. Group B, the placebo group, receives Placebo plus standard treatment.

One site, in Hamilton

Phase 3
2 groups
One site, in Hamilton
Recruiting

Official title: Multiprofen-CC to Reduce Pain in Hand Arthritis

Hand Osteoarthritis · St. Joseph's Healthcare Hamilton

Comparing Prednisone with Adalimumab for inflammatory arthritis

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There are 2 groups in this study. Group A, the comparison group, receives one or more of: Adalimumab and Prednisone. Group B, the comparison group, receives Adalimumab.

One site, in London

Phase 2
2 groups
One site, in London
Recruiting

Official title: Early Adalimumab Induction for Immune Checkpoint Inhibitor Associated Inflammatory Arthritis

Inflammatory Arthritis · Tom Appleton

Testing CBD against a placebo for osteoarthritis of knee

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There are 3 groups in this study. Group A receives CBD. Group B receives THC. Group C, the placebo group, receives Placebo.

Sites in Toronto and Montreal

3 groups
Sites in Toronto and Montreal
Recruiting

Official title: Cannabinoids for Osteoarthritis Pain Effectiveness Trial

Osteoarthritis of Knee · University Health Network, Toronto

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Concord provides information support only. Trial listings come from public registries; eligibility is always determined by the trial site and your care team.