Rheumatoid Arthritis Clinical Trials

Trials for someone you care about with rheumatoid arthritis.

Arthritis & Autoimmune

Recruiting Drug Device Behavioral Older adults Healthy volunteers

25 trials

Testing Eloralintide against a placebo for osteoarthritis

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There are 4 groups in this study. Groups A and C receive Eloralintide. Groups B and D, the placebo group, receive Placebo.

Sites in Québec, Toronto and 3 more cities

Phase 3
4 groups
Sites in Guelph, Québec and 3 more cities
Recruiting

Official title: Efficacy and Safety of Eloralintide (LY3841136) in Participants With Osteoarthritis Knee Pain and Obesity or Overweight

Osteoarthritis · Eli Lilly and Company

Testing Hydroxychloroquine against a placebo for arthritis

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There are 2 groups in this study. Group A receives Hydroxychloroquine. Group B, the placebo group, receives Placebo.

One site, in Edmonton

Phase 2
2 groups
One site, in Edmonton
Recruiting

Official title: Immune-Mediated Pathophysiology And Clinical Triage Program

Arthritis · AHS Cancer Control Alberta

Testing Tulisokibart against a placebo for radiographic axial spondyloarthritis

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There are 4 groups in this study. Groups A, B and C receive Tulisokibart. Group D, the placebo group, receives Placebo.

Sites in Québec, Toronto and 1 more city

Phase 2
4 groups
Sites in Toronto, Québec and 1 more city
Recruiting

Official title: A Clinical Study of Tulisokibart (MK-7240) to Treat Radiographic Axial Spondyloarthritis (MK-7240-013)

Radiographic Axial Spondyloarthritis · Merck Sharp & Dohme LLC

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Testing Bimekizumab for enthesitis-related arthritis

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Everyone in this study is in one group and receives Bimekizumab.

Sites in Calgary, Montreal and 1 more city

Phase 3
1 group
Sites in Calgary, Montreal and 1 more city
Recruiting

Official title: An Open-label Study to Evaluate the Pharmacokinetics and Safety of Bimekizumab in Pediatric Study Participants With Active Juvenile Idiopathic Arthritis Subtypes Enthesitis-related Arthritis (Including Juvenile-onset Ankylosing Spondylitis) and Juvenile Psoriatic Arthritis

Enthesitis-related Arthritis · UCB Biopharma SRL

Testing AZD1163 against a placebo for rheumatoid arthritis

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There are 4 groups in this study. Groups A, B and C receive AZD1163. Group D, the placebo group, receives Placebo.

Sites in Niagara Falls, Ottawa and 2 more cities

Phase 2
4 groups
Sites in Niagara Falls, Ottawa and 2 more cities
Recruiting

Official title: A Study to Investigate Efficacy and Safety of AZD1163 in Participants With Rheumatoid Arthritis

Rheumatoid Arthritis · AstraZeneca

Testing Lutikizumab against a placebo for rheumatoid arthritis

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There are 6 groups in this study. Group A receives Lutikizumab. Groups B, D and F, the placebo group, receive Placebo. Group C receives Ravagalimab. …and 1 more groups.

Sites in Calgary, Saskatoon and 1 more city

Phase 2
6 groups
Sites in Calgary, Sherbrooke and 1 more city
Recruiting

Official title: A Study to Evaluate Different Targeted Therapies for Patients With Rheumatoid Arthritis

Rheumatoid Arthritis · AbbVie

Testing Icotrokinra against a placebo for psoriatic arthritis

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There are 3 groups in this study. Groups A and B receive Icotrokinra. Group C, the placebo group, receives Placebo, together with one or more of: Icotrokinra.

Sites in Montreal, Orillia and 5 more cities

Phase 3
3 groups
Sites in St. John's, Orillia and 5 more cities
Recruiting

Official title: A Study to Evaluate the Efficacy and Safety of Icotrokinra (JNJ-77242113) in Biologic-experienced and Biologic-naive Participants With Active Psoriatic Arthritis

Arthritis, Psoriatic · Janssen Research & Development, LLC

Comparing targeted synthetic DMARD class with non-TNFi-biologic class for rheumatoid arthritis

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There are 2 groups in this study. Group A, the comparison group, receives targeted synthetic DMARD class. Group B, the comparison group, receives non-TNFi-biologic class.

One site, in Toronto

Phase 3
2 groups
One site, in Toronto
Recruiting

Official title: RA-PRO PRAGMATIC TRIAL

Rheumatoid Arthritis · University of Alabama at Birmingham

Testing Orforglipron against a placebo for osteoarthritis

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There are 4 groups in this study. Groups A and C receive Orforglipron. Groups B and D, the placebo group, receive Placebo.

Sites in Québec, Brampton and 4 more cities

Phase 3
4 groups
Sites in Brampton, Joliette and 4 more cities
Recruiting

Official title: A Study of Orforglipron (LY3502970) in Participants With Obesity or Overweight and Osteoarthritis (OA) of the Knee

Osteoarthritis · Eli Lilly and Company

Testing Tulisokibart against a placebo for psoriatic arthritis

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There are 4 groups in this study. Groups A, B and C receive Tulisokibart. Group D, the placebo group, receives Placebo.

Sites in Rimouski and Trois-Rivières

Phase 2
4 groups
Sites in Rimouski and Trois-Rivières
Recruiting

Official title: Study to Evaluate Tulisokibart in Adults With Psoriatic Arthritis (MK-7240-015)

Psoriatic Arthritis · Merck Sharp & Dohme LLC

Testing Sonelokimab against a placebo for psoriatic arthritis

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There are 4 groups in this study. Groups A and B receive Sonelokimab. Group C, the placebo group, receives Placebo. Group D, the comparison group, receives Risankizumab.

Sites in Calgary, Toronto and 3 more cities

Phase 3
4 groups
Sites in Toronto, Calgary and 3 more cities
Recruiting

Official title: Evaluation of Sonelokimab in Patients With Active Psoriatic Arthritis and Anti-TNFα Inadequate Response

Arthritis, Psoriatic · MoonLake Immunotherapeutics AG

Comparing 3 approaches for psoriatic arthritis

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There are 3 groups in this study. Groups A and B receive Zasocitinib. Group C receives Placebo, together with one or more of: Zasocitinib.

Sites in Niagara Falls, Québec and 1 more city

Phase 3
3 groups
Sites in Niagara Falls, Toronto and 1 more city
Recruiting

Official title: A Study of Zasocitinib in Adults With Psoriatic Arthritis Who Have or Have Not Been Treated With Biologic Medicines

Psoriatic Arthritis · Takeda

Testing Glucocorticoid (GC) for rheumatoid arthritis (RA)

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There are 2 groups in this study. Groups A and B receive Glucocorticoid (GC).

5 sites in Toronto

Phase 4
2 groups
5 sites in Toronto
Recruiting

Official title: Oral Versus Intramuscular Steroid Use to Control Rheumatoid Arthritis Flares

Rheumatoid Arthritis (RA) · Sunnybrook Health Sciences Centre

Comparing 3 approaches for psoriatic arthritis

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There are 3 groups in this study. Group A receives Risankizumab. Group B receives Lutikizumab. Group C receives Lutikizumab and Risankizumab.

Sites in Saskatoon and Trois-Rivières

Phase 2
3 groups
Sites in Trois-Rivières and Saskatoon
Recruiting

Official title: Study of Targeted Therapies for the Treatment of Adult Participants With Active Psoriatic Arthritis

Psoriatic Arthritis · AbbVie

Testing Upadacitinib against a placebo for psoriatic arthritis

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There are 2 groups in this study. Group A receives Upadacitinib 15 MG [Rinvoq]. Group B, the placebo group, receives Placebo.

Sites in Ottawa and Québec

Phase 4
2 groups
Sites in Ottawa and Québec
Recruiting

Official title: A Study to Evaluate the Impact of Upadacitinib on Spondyloarthritis Outcomes in Patients With Active Psoriatic Arthritis

Psoriatic Arthritis · CARE ARTHRITIS LTD.

Comparing Risankizumab with Adalimumab for juvenile psoriatic arthritis

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There are 2 groups in this study. Group A receives Risankizumab. Group B receives Adalimumab.

Sites in Calgary, Toronto and 1 more city

Phase 3
2 groups
Sites in Calgary, Vancouver and 1 more city
Recruiting

Official title: A Study to Assess Adverse Events, Change in Disease Activity, and How the Drug Moves Through the Body in Children With Juvenile Psoriatic Arthritis (jPsA) Receiving Subcutaneously Injected Risankizumab or Adalimumab

Juvenile Psoriatic Arthritis · AbbVie

Comparing 4 approaches for rheumatoid arthritis

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There are 4 groups in this study. Group A, the comparison group, receives TNFi. Groups B and C, the comparison group, receive Anti-IL6. Group D, the comparison group, receives JAKi.

One site, in Montreal

4 groups
One site, in Montreal
Recruiting

Official title: Stand UP to Rheumatoid Arthritis (SUPRA)

Rheumatoid Arthritis · Marie Hudson, MD

Comparing Etanercept with tofacitinib for rheumatoid arthritis

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There are 2 groups in this study. Group A, the comparison group, receives Etanercept. Group B, the comparison group, receives tofacitinib.

One site, in London

Phase 4
2 groups
One site, in London
Recruiting

Official title: Advanced Therapeutics in Rheumatoid Arthritis (RA)

Rheumatoid Arthritis · London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's

Testing Duloxetine against a placebo for knee osteoarthritis

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There are 2 groups in this study. Group A receives Duloxetine. Group B, the placebo group, receives Placebo.

2 sites in Toronto

Phase 4
2 groups
2 sites in Toronto
Recruiting

Official title: Effect of peRiopErative duLoxetIne Administration on Opioid Consumption Following Total kneE Arthroplasty (RELIFE)

Knee Osteoarthritis · Sunnybrook Health Sciences Centre

Comparing Physical Therapy with Hyaluronic and corticosteroid for osteoarthritis

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There are 2 groups in this study. Group A receives Hyaluronic and corticosteroid injection and Physical Therapy. Group B, the comparison group, receives Hyaluronic and corticosteroid injection.

One site, in Hamilton

2 groups
One site, in Hamilton
Recruiting

Official title: Intra-articular Corticosteroid With Hyaluronic Acid Plus Physiotherapy for Hip Pathologies (NON-OP HIP)

Osteoarthritis · ArthroBiologix Inc.

Testing Sarilumab SAR153191 for juvenile idiopathic arthritis

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Everyone in this study is in one group and receives Sarilumab SAR153191 (REGN88).

One site, in Calgary

Phase 2
1 group
One site, in Calgary
Recruiting

Official title: A Repeated Dose-finding Study of Sarilumab in Children and Adolescents With Systemic Juvenile Idiopathic Arthritis (SKYPS)

Juvenile Idiopathic Arthritis · Sanofi

Testing Triamcinolone Acetonide for trapeziometacarpal osteoarthritis

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There are 2 groups in this study. Group A receives Saline Solution (NaCl 0,9%). Group B, the comparison group, receives Triamcinolone Acetonide.

2 sites in Montreal

Phase 2
2 groups
2 sites in Montreal
Recruiting

Official title: Corticosteroid Against Saline Injections for Thumb Osteoarthritis (CASITOA)

Trapeziometacarpal Osteoarthritis · Université du Québec à Trois-Rivières

Testing Multiprofen-CC™ plus standard treatment against a placebo for hand osteoarthritis

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There are 2 groups in this study. Group A receives Multiprofen-CC™ plus standard treatment. Group B, the placebo group, receives Placebo plus standard treatment.

One site, in Hamilton

Phase 3
2 groups
One site, in Hamilton
Recruiting

Official title: Multiprofen-CC to Reduce Pain in Hand Arthritis

Hand Osteoarthritis · St. Joseph's Healthcare Hamilton

Comparing Prednisone with Adalimumab for inflammatory arthritis

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There are 2 groups in this study. Group A, the comparison group, receives one or more of: Adalimumab and Prednisone. Group B, the comparison group, receives Adalimumab.

One site, in London

Phase 2
2 groups
One site, in London
Recruiting

Official title: Early Adalimumab Induction for Immune Checkpoint Inhibitor Associated Inflammatory Arthritis

Inflammatory Arthritis · Tom Appleton

Testing CBD against a placebo for osteoarthritis of knee

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There are 3 groups in this study. Group A receives CBD. Group B receives THC. Group C, the placebo group, receives Placebo.

Sites in Toronto and Montreal

3 groups
Sites in Toronto and Montreal
Recruiting

Official title: Cannabinoids for Osteoarthritis Pain Effectiveness Trial

Osteoarthritis of Knee · University Health Network, Toronto

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Concord provides information support only. Trial listings come from public registries; eligibility is always determined by the trial site and your care team.