Rheumatoid Arthritis Clinical Trials

Official title: Adapting Rehabilitation Delivery for Maximum Impact at Home-2 (ReDI-2)

Knee Osteoarthritis · University of Alberta

Testing Tulisokibart against a placebo for radiographic axial spondyloarthritis

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Sites in Québec, Toronto and 1 more city

Official title: A Clinical Study of Tulisokibart (MK-7240) to Treat Radiographic Axial Spondyloarthritis (MK-7240-013)

Radiographic Axial Spondyloarthritis · Merck Sharp & Dohme LLC

Comparing 3 approaches for psoriatic arthritis

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Sites in Niagara Falls, Québec and 1 more city

Official title: A Study of Zasocitinib in Adults With Psoriatic Arthritis Who Have or Have Not Been Treated With Biologic Medicines

Psoriatic Arthritis · Takeda

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Testing Orforglipron against a placebo for osteoarthritis

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Sites in Québec, Brampton and 4 more cities

Official title: A Study of Orforglipron (LY3502970) in Participants With Obesity or Overweight and Osteoarthritis (OA) of the Knee

Osteoarthritis · Eli Lilly and Company

Testing Eloralintide against a placebo for osteoarthritis

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Sites in Québec, Toronto and 3 more cities

Official title: Efficacy and Safety of Eloralintide (LY3841136) in Participants With Osteoarthritis Knee Pain and Obesity or Overweight

Osteoarthritis · Eli Lilly and Company

Comparing Etanercept with tofacitinib for rheumatoid arthritis

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One site, in London

Official title: Advanced Therapeutics in Rheumatoid Arthritis (RA)

Rheumatoid Arthritis · London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's

Testing Hydroxychloroquine against a placebo for arthritis

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One site, in Edmonton

Official title: Immune-Mediated Pathophysiology And Clinical Triage Program

Arthritis · AHS Cancer Control Alberta

Comparing targeted synthetic DMARD class with non-TNFi-biologic class for rheumatoid arthritis

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One site, in Toronto

Official title: RA-PRO PRAGMATIC TRIAL

Rheumatoid Arthritis · University of Alabama at Birmingham

Comparing 4 approaches for rheumatoid arthritis

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One site, in Montreal

Official title: Stand UP to Rheumatoid Arthritis (SUPRA)

Rheumatoid Arthritis · Marie Hudson, MD

Comparing Risankizumab with Adalimumab for juvenile psoriatic arthritis

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Sites in Calgary, Toronto and 1 more city

Official title: A Study to Assess Adverse Events, Change in Disease Activity, and How the Drug Moves Through the Body in Children With Juvenile Psoriatic Arthritis (jPsA) Receiving Subcutaneously Injected Risankizumab or Adalimumab

Juvenile Psoriatic Arthritis · AbbVie

Testing Upadacitinib against a placebo for psoriatic arthritis

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Sites in Ottawa and Québec

Official title: A Study to Evaluate the Impact of Upadacitinib on Spondyloarthritis Outcomes in Patients With Active Psoriatic Arthritis

Psoriatic Arthritis · CARE ARTHRITIS LTD.

Testing Sonelokimab against a placebo for psoriatic arthritis

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Sites in Calgary, Toronto and 3 more cities

Official title: Evaluation of Sonelokimab in Patients With Active Psoriatic Arthritis and Anti-TNFα Inadequate Response

Arthritis, Psoriatic · MoonLake Immunotherapeutics AG

Testing Bimekizumab for enthesitis-related arthritis

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Sites in Calgary, Montreal and 1 more city

Official title: An Open-label Study to Evaluate the Pharmacokinetics and Safety of Bimekizumab in Pediatric Study Participants With Active Juvenile Idiopathic Arthritis Subtypes Enthesitis-related Arthritis (Including Juvenile-onset Ankylosing Spondylitis) and Juvenile Psoriatic Arthritis

Enthesitis-related Arthritis · UCB Biopharma SRL

Testing Icotrokinra against a placebo for psoriatic arthritis

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Sites in Montreal, Orillia and 5 more cities

Official title: A Study to Evaluate the Efficacy and Safety of Icotrokinra (JNJ-77242113) in Biologic-experienced and Biologic-naive Participants With Active Psoriatic Arthritis

Arthritis, Psoriatic · Janssen Research & Development, LLC

Comparing 3 approaches for psoriatic arthritis

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Sites in Saskatoon and Trois-Rivières

Official title: Study of Targeted Therapies for the Treatment of Adult Participants With Active Psoriatic Arthritis

Psoriatic Arthritis · AbbVie

Testing Lutikizumab against a placebo for rheumatoid arthritis

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Sites in Calgary, Saskatoon and 1 more city

Official title: A Study to Evaluate Different Targeted Therapies for Patients With Rheumatoid Arthritis

Rheumatoid Arthritis · AbbVie

Testing Glucocorticoid (GC) for rheumatoid arthritis (RA)

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5 sites in Toronto

Official title: Oral Versus Intramuscular Steroid Use to Control Rheumatoid Arthritis Flares

Rheumatoid Arthritis (RA) · Sunnybrook Health Sciences Centre

Testing AZD1163 against a placebo for rheumatoid arthritis

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Sites in Trois-Rivières and Windsor

Official title: A Study to Investigate Efficacy and Safety of AZD1163 in Participants With Rheumatoid Arthritis

Rheumatoid Arthritis · AstraZeneca

Testing Tulisokibart against a placebo for psoriatic arthritis

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Sites in Rimouski and Trois-Rivières

Official title: Study to Evaluate Tulisokibart in Adults With Psoriatic Arthritis (MK-7240-015)

Psoriatic Arthritis · Merck Sharp & Dohme LLC

Testing bariatric surgery followed by total for knee osteoarthritis

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One site, in Halifax

Official title: Optimal Management of Extreme Obesity and Severe Knee Osteoarthritis Feasibility Trial

Knee Osteoarthritis · Nova Scotia Health Authority

Comparing XPERIENCE Advanced Surgical Irrigation with Dilute Betadine for hip osteoarthritis

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Sites in Montreal, Toronto and 4 more cities

Official title: Evaluating XPERIENCE™ Advanced Surgical Irrigation

Hip Osteoarthritis · Ottawa Hospital Research Institute

Testing Primary Care Rheumatology Family for rheumatoid arthritis

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One site, in Waterloo

Official title: Comorbidity Management in Rheumatic Disease.

Rheumatoid Arthritis · Western University, Canada

Testing Duloxetine against a placebo for knee osteoarthritis

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2 sites in Toronto

Official title: Effect of peRiopErative duLoxetIne Administration on Opioid Consumption Following Total kneE Arthroplasty (RELIFE)

Knee Osteoarthritis · Sunnybrook Health Sciences Centre

Comparing M3 Intervention group with M3 Waitlist Group for juvenile idiopathic arthritis

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Sites in Hamilton, London and 1 more city

Official title: M3-JIA: Making Mindfulness Matter for Children With JIA

Juvenile Idiopathic Arthritis · London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's

Testing Choose to Move Replacement Ready for osteoarthritis

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One site, in Vancouver

Official title: Feasibility of Choose to Move Replacement Ready

Osteoarthritis · University of British Columbia

Testing Choose to Move Replacement Ready for osteoarthritis (OA)

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One site, in Vancouver

Official title: Evaluation of Choose to Move Replacement Ready (CTM-RR)

Osteoarthritis (OA) · University of British Columbia

Comparing Eccentric Reaming with Posterior Glenoid Bone Grafting for shoulder osteoarthritis

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One site, in Ottawa

Official title: TSA Techniques in Glenohumeral OA

Osteoarthritis, Shoulder · Ottawa Hospital Research Institute

Testing FitJoints Multi-modal Intervention for hip osteoarthritis

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Sites in Hamilton, Calgary and 1 more city

Official title: FitJoints: Getting Fit for Hip and Knee Replacement

Hip Osteoarthritis · McMaster University

Testing Yoga against a placebo for knee osteoarthritis

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Sites in Hamilton, London and 1 more city

Official title: Transcranial Direct Current Stimulation and Yoga for Knee Osteoarthritis

Knee Osteoarthritis · McMaster University

Comparing RTSA with subscapularis repair with RTSA without subscapularis repair for arthritis shoulder

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One site, in Winnipeg