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Testing Prism Adaptation - 15-degree prism with Prism Adaptation - 5-degree prism against a placebo for spatial neglect

Official title: Engaging Mobile Prism Adaptation Treatment at Home

Feasibility and Effectiveness of a New Computerized Treatment Protocol for Spatial Neglect Post Stroke During Inpatient and Outpatient Rehabilitation

Condition: Spatial NeglectSponsor: Nova Scotia Health AuthorityTarget enrollment: 80
  • 2 groups
  • Sites in Bedford, Halifax and 1 more city
  • Recruiting
Nova Scotia Rehabilitation and Arthritis Centre (NSRAC), Halifax, Nova ScotiaNova Scotia Health Early Supported Stroke Discharge Team, Bedford, Nova ScotiaNova Scotia Rehabilitation and Arthritis Centre, Halifax, Nova ScotiaValley Regional Hospital, Kentville, Nova Scotia

Interventions

  • Behavioural therapy

    Prism Adaptation - 15-degree prism goggles

    Patients in the experimental condition will wear prism goggles while completing an iPad-administered aiming task. The prisms will shift the patients' vision 15 degrees rightward, causing a recalibration of visuo-motor information. Prism adaptation will be carried out for ten sessions for 15 minutes a day, over the span of two weeks.

  • Other intervention

    Prism Adaptation - 5-degree prism goggles

    5-degree goggles are worn instead of the 15-degree prism goggles, while completing the same tasks as those assigned to the 15-degree condition.

Canadian Sites (4)

3 of 4 recruiting

  • Nova Scotia Health Early Supported Stroke Discharge Team

    Bedford, Nova Scotia

    Recruiting
  • Nova Scotia Rehabilitation and Arthritis Centre

    Halifax, Nova Scotia

    Recruiting
  • Valley Regional Hospital

    Kentville, Nova Scotia

    Recruiting

Eligibility Criteria

See who this study is looking for8 criteria

The trial’s own eligibility text, word for word from the registry. Only the trial site can say who takes part.

Inclusion

  • +Have experienced a right hemisphere stroke (confirmed by a clinician)
  • +Experience mild to severe symptoms of neglect
  • +Be willing and able to consentInformed consentThe process of being told what taking part involves, then choosing freely.Read more → to participate
  • +Be medically stable
  • +Have self-reported normal to corrected-to-normal vision
  • +Be able to point to targets presented on a computer screen
  • +Live within a two-hour radius of Halifax

Exclusion

  • Other existing neurological disorders (e.g., dementia, multiple sclerosis, epilepsy).
5 concepts to explore on this page · up to 1,300 pointsTap any term to learn what it means.

In plain language

Assembled directly from this trial’s registry record. Every sentence traces to a field below — nothing here is generated or interpreted.

Learning 
What this study is

This study is testing a treatment for a condition.

This study is not organised into the usual phase numbers — that is common for device, behavioural, and diagnostic research.

From the trial registry

Built from these fields:

  • designModule.designInfo.primaryPurpose
  • designModule.phases
Who receives what

There are 2 groups in this study.

Group A receives Prism Adaptation - 15-degree prism goggles.

Registry label: A: Prism adaptation treatment

Group B, the placeboPlaceboA dummy treatment with no active medicine, used for comparison.Read more → group, receives Prism Adaptation - 5-degree prism goggles.

Registry label: B: Placebo control prism adaptation treatment

From the trial registry

Built from these fields:

  • armsInterventionsModule.armGroups[].label
  • armsInterventionsModule.armGroups[].type
  • armsInterventionsModule.armGroups[].interventionNames
How the study is run

Which group you would be placed in is decided by chance, like a coin flip — not by you and not by your doctor.

Neither you nor the study team would know which group you are in until the study ends.

From the trial registry

Built from these fields:

  • designModule.designInfo.allocation
  • designModule.designInfo.maskingInfo.masking
Is there a placebo?

One group receives a placeboPlaceboA dummy treatment with no active medicine, used for comparison.Read more → — a dummy treatment with no active medicine in it.

From the trial registry

Built from these fields:

  • armsInterventionsModule.armGroups[].type
  • armsInterventionsModule.armGroups[].interventionNames
Who the study is looking for

The study is open to people of any sex.

The study does not accept healthy volunteersHealthy volunteerSomeone without the condition being studied who takes part anyway.Read more →.

These are the criteria the study lists. Only the trial siteTrial siteA hospital or clinic where a study is actually run.Read more → can decide whether someone can take part.

From the trial registry

Built from these fields:

  • eligibilityModule.sex
  • eligibilityModule.healthyVolunteers
How big and how long

The study aims to enrol about 80 people.

The study is currently expected to finish around November 2026.

The main measurement is taken over: taken at baselineBaselineYour starting measurements, taken before treatment begins.Read more → (immediately before the intervention), immediately after the intervention, and one month after the intervention.

From the trial registry

Built from these fields:

  • designModule.enrollmentInfo.count
  • statusModule.completionDateStruct.date
  • outcomesModule.primaryOutcomes[].timeFrame
What the study measures

Test of neglect severity 1 — measured over taken at baselineBaselineYour starting measurements, taken before treatment begins.Read more → (immediately before the intervention), immediately after the intervention, and one month after the intervention.

Test of neglect severity 2 — measured over measured immediately before and immediately after each intervention session.

Test of neglect severity 3 — measured over taken at baseline (immediately before the intervention), immediately after the intervention, and one month after the intervention.

Test of neglect impact on daily activities — measured over taken at baseline (immediately before the intervention), immediately after the intervention, and one month after the intervention.

The study lists 3 further main measurements.

From the trial registry

Built from these fields:

  • outcomesModule.primaryOutcomes[].measure
  • outcomesModule.primaryOutcomes[].timeFrame

Source: NCT05595668 on ClinicalTrials.gov. The full registry text is further down this page — this summary never replaces it.

Not medical advice. What do these terms mean?

What is being tested — in plain terms

About Prism Adaptation - 15-degree prism gogglesBehavioural

Patients in the experimental condition will wear prism goggles while completing an iPad-administered aiming task. The prisms will shift the patients' vision 15 degrees rightward, causing a recalibration of visuo-motor information. Prism adaptation will be carried out for ten sessions for 15 minutes a day, over the span of two weeks.

From the trial registry — its own words, unedited.

What a behavioural is here: A programme, therapy, education, or lifestyle approach being studied.

Read the full explanation → · in clinical review

About Prism Adaptation - 5-degree prism gogglesOther

5-degree goggles are worn instead of the 15-degree prism goggles, while completing the same tasks as those assigned to the 15-degree condition.

From the trial registry — its own words, unedited.

What a other is here: An intervention the registry did not place in another category.

Read the full explanation → · in clinical review

Common questions

Answered from this trial’s registry record. Where the record doesn’t say, these answers say so rather than filling the gap.

Am I eligible for this trial?

Only the trial siteTrial siteA hospital or clinic where a study is actually run.Read more → can decide whether someone can take part. Concord cannot make that determination, and neither can any tool that has not examined you.

The full inclusionInclusion criteriaThe things you must have or be for a study to consider you.Read more → and exclusion criteriaExclusion criteriaThe things that would prevent someone from taking part.Read more → are published on this page, exactly as the study team wrote them.

The useful next step is to bring this trial to your doctor. Answering a few questions first gives them something concrete to review.

From the trial registry
  • eligibilityModule.eligibilityCriteria
Is there a placebo?

Yes. This study includes a placeboPlaceboA dummy treatment with no active medicine, used for comparison.Read more → group — a dummy treatment with no active medicine in it.

From the trial registry
  • armsInterventionsModule.armGroups[].type
Would I know which treatment I am getting?

Neither you nor the study team would know which group you are in until the study ends.

Which group you would be placed in is decided by chance, like a coin flip — not by you and not by your doctor.

From the trial registry
  • designModule.designInfo.maskingInfo.masking
  • designModule.designInfo.allocation
Who can join?

It is open to people of any sex.

It does not accept healthy volunteersHealthy volunteerSomeone without the condition being studied who takes part anyway.Read more →.

Only the trial siteTrial siteA hospital or clinic where a study is actually run.Read more → can confirm whether a particular person can take part.

From the trial registry
  • eligibilityModule.sex
  • eligibilityModule.healthyVolunteers
How long would this take?

The study's main measurement is taken over: taken at baselineBaselineYour starting measurements, taken before treatment begins.Read more → (immediately before the intervention), immediately after the intervention, and one month after the intervention.

The study as a whole is currently expected to finish around 2026-11.

How long any one person takes part can differ from the study length. The study team can tell you what the schedule looks like in practice.

From the trial registry
  • outcomesModule.primaryOutcomes[].timeFrame
  • statusModule.completionDateStruct.date
How many people are taking part?

The study aims to enrol about 80 people.

From the trial registry
  • designModule.enrollmentInfo.count
Where is this happening?

This study lists 3 locations, including: Bedford, Nova Scotia, Canada; Halifax, Nova Scotia, Canada; Kentville, Nova Scotia, Canada.

Sites can open and close during a study, so confirm with the team before travelling.

From the trial registry
  • trial_locations

About This Trial

Spatial neglect is a common disorder after stroke which leads to problems with noticing or responding to information from the left side of the body or space. This condition has been linked to reduced independence in a wide range of daily life activities including eating, dressing, and mobility. Despite its high prevalence in stroke patients, there is currently no standard of care for spatial neglect. Prism adaptation (PA) is a promising treatment, however, there are limitations to using PA in standard clinical care as it requires daily exposure for at least two weeks, yet access to equipment and supervision is limited. To solve this problem, the investigators have developed a new game-like PA treatment (Peg-the-Mole, PTM) that can be used at home without the need for daily in person therapist set-up and supervision. In this study the investigators aim to evaluate the feasibility and effectiveness of the gamified and portable PA procedure in an inpatient and home setting, with the hypothesis that the PA procedure will improve patient's neglect symptoms.

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This page is for informational purposes only and does not constitute medical advice. Clinical trial eligibility can only be determined by the trial site after proper screening. Trial information is sourced from ClinicalTrials.gov and may not reflect the most current status. Always consult your healthcare provider before making decisions about clinical trial participation.