Phase 1
The earliest stage of human testing, in a small group, focused on safety.
What it means
Phase 1 studies are usually the first time a treatment is given to people. They enrol a small number of participants and focus on safety, tolerability, and finding a workable dose.
Why it matters if you take part
The main question is how the treatment is tolerated, not whether it works. Phase 1 studies often involve more frequent visits and more monitoring than later phases.
Related terms
Trials recruiting now that are Phase 1
334 recruiting trials in our Canadian corpus are Phase 1.
A Study Evaluating the Safety and Efficacy of Targeted Therapies in Subpopulations of Patients With Metastatic Colorectal Cancer (INTRINSIC)
Metastatic Colorectal Cancer · PHASE1
A First-in-human Study of KK8123 in Adults With X-linked Hypophosphatemia
X-linked Hypophosphatemia · PHASE1
A Study of VRN110755 in Patients With EGFR-Mutant Non-Small Cell Lung Cancer
EGFR-Mutant Non-Small Cell Lung Cancer · PHASE1
A Study of Neladalkib (NVL-655) in Patients With Advanced NSCLC and Other Solid Tumors Harboring ALK Rearrangement or Activating ALK Mutation (ALKOVE-1)
Locally Advanced Solid Tumor · PHASE1
A Study of ERAS-0015 in Patients With Advanced or Metastatic Solid Tumors
Metastatic Solid Tumors · PHASE1
A Study to Evaluate the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics, and Efficacy of NXT007 in Persons With Severe or Moderate Hemophilia A
Hemophilia A · PHASE1
This explains how clinical research works. It is not medical advice and does not describe any specific condition or treatment. Only a trial site can determine whether someone can take part in a study.