Type 2 Diabetes Clinical Trials

Trials for someone you care about with type 2 diabetes.

Diabetes & Hormones

Recruiting Drug Device Behavioral Older adults Healthy volunteers

46 trials · showing 30

Comparing Maridebart cafraglutide with Semaglutide for type 2 diabetes mellitus

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There are 2 groups in this study. Group A receives Maridebart cafraglutide. Group B, the comparison group, receives Semaglutide.

One site, in Vancouver

Phase 3
2 groups
One site, in Vancouver
Recruiting

Official title: Maridebart Cafraglutide Versus Semaglutide in Participants With Type 2 Diabetes

Diabetes Mellitus, Type 2 · Amgen

Testing Baricitinib against a placebo for type 1 diabetes mellitus

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There are 2 groups in this study. Group A receives Baricitinib. Group B, the placebo group, receives Placebo.

Sites in Calgary, Chicoutimi and 5 more cities

Phase 3
2 groups
Sites in Calgary, Chicoutimi and 5 more cities
Recruiting

Official title: A Study of Baricitinib (LY3009104) to Preserve Beta Cell Function in Children and Adults Newly Diagnosed With Type 1 Diabetes (BARICADE-PRESERVE)

Diabetes Mellitus, Type 1 · Eli Lilly and Company

Testing Baricitinib against a placebo for type 1 diabetes mellitus

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There are 2 groups in this study. Group A receives Baricitinib. Group B, the placebo group, receives Placebo.

Sites in Calgary, Edmonton and 1 more city

Phase 3
2 groups
Sites in Calgary, Edmonton and 1 more city
Recruiting

Official title: A Study of Baricitinib (LY3009104) for the Delay of Stage 3 Type 1 Diabetes in At-Risk Children and Adults

Diabetes Mellitus, Type 1 · Eli Lilly and Company

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Testing LY3457263 against a placebo for type 2 diabetes

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There are 4 groups in this study. Groups A, B and C receive LY3457263. Group D, the placebo group, receives Placebo.

Sites in Toronto, Brampton and 6 more cities

Phase 2
4 groups
Sites in Brampton, Chicoutimi and 6 more cities
Recruiting

Official title: A Study of LY3457263 Compared With Placebo in Participants With Type 2 Diabetes on a Stable Dose of Semaglutide or Tirzepatide

Type 2 Diabetes · Eli Lilly and Company

Comparing Exercise with BFR with Exercise for type 2 diabetes

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There are 2 groups in this study. Group A receives Exercise with BFR. Group B, the comparison group, receives Exercise.

One site, in Kelowna

2 groups
One site, in Kelowna
Recruiting

Official title: 6-Weeks of Blood Flow Restriction Training on Immune Cell Function and Bioenergetics

Type 2 Diabetes · University of British Columbia

Testing Survodutide against a placebo for type 2 diabetes

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There are 9 groups in this study. Groups A, D and G, the placebo group, receive Placebo. Groups B, C, E, F, H and I receive Survodutide.

Sites in Toronto, Montreal and 5 more cities

Phase 3
9 groups
Sites in New Westminster, Brampton and 5 more cities
Recruiting

Official title: A Study to Test Whether Survodutide Helps People With Type 2 Diabetes Control Their Blood Sugar

Type 2 Diabetes · Boehringer Ingelheim

Comparing Vicadrostat with Empagliflozin for type 2 diabetes mellitus

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There are 2 groups in this study. Group A receives Vicadrostat and Empagliflozin. Group B, the comparison group, receives Empagliflozin, together with one or more of: Placebo matching Vicadrostat.

Sites in Toronto, Montreal and 29 more cities

Phase 3
2 groups
Sites in Calgary, Red Deer and 29 more cities
Recruiting

Official title: EASi-PROTKT™ - A Study to Test Vicadrostat (BI 690517) Taken Together With Empagliflozin in People With Type 2 Diabetes, High Blood Pressure, and Cardiovascular Disease

Diabetes Mellitus, Type 2 · Boehringer Ingelheim

Comparing Elecoglipron with Semaglutide for type 2 diabetes mellitus

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There are 2 groups in this study. Group A receives Elecoglipron. Group B, the comparison group, receives Semaglutide.

Sites in Toronto, Guelph and 6 more cities

Phase 3
2 groups
Sites in Vancouver, Guelph and 6 more cities
Recruiting

Official title: A Study to Find Out if the Study Drug Elecoglipron Helps Adults With Type 2 Diabetes Mellitus by Comparing it With Semaglutide, a Medicine Already Used to Treat Type 2 Diabetes Mellitus

Type 2 Diabetes Mellitus · AstraZeneca

Comparing Health coaching with Educational emails for type 2 diabetes

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There are 2 groups in this study. Group A receives Health coaching. Group B, the comparison group, receives Educational emails.

Sites in Hamilton and Toronto

2 groups
Sites in Hamilton and Toronto
Recruiting

Official title: Technology-Enabled Collaborative Care for Diabetes and Mental Health

Type 2 Diabetes · McMaster University

Testing Teplizumab against a placebo for type 1 diabetes mellitus

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There are 2 groups in this study. Group A receives Teplizumab. Group B, the placebo group, receives Placebo.

Sites in Calgary, Halifax and 2 more cities

Phase 3
2 groups
Sites in Calgary, Vancouver and 2 more cities
Recruiting

Official title: A Study to Investigate Efficacy and Safety of Teplizumab Compared With Placebo in Participants 1 to 25 Years of Age With Stage 3 Type 1 Diabetes

Type 1 Diabetes Mellitus · Sanofi

Testing Fish Oil against a placebo for type 2 diabetes

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There are 3 groups in this study. Groups A and B, the comparison group, receive Fish Oil. Group C, the placebo group, receives Corn oil control.

One site, in Montreal

Phase 2
3 groups
One site, in Montreal
Recruiting

Official title: Effects of Different Fish Oil Types on Type 2 Diabetes Risk Factors in High-Risk Adults

Type 2 Diabetes · May Faraj, PDt, PhD

Comparing 3 approaches for type 1 diabetes mellitus

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There are 3 groups in this study. Groups A, B and C receive VV-14300.

One site, in Toronto

Phase 1
3 groups
One site, in Toronto
Recruiting

Official title: VV-14300 for the Treatment of Type 1 Diabetes

Type 1 Diabetes Mellitus · Kriya Therapeutics, Inc.

Testing Kefir for gestational diabetes mellitus (GDM)

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There are 2 groups in this study. Group A receives Kefir. Group B receives no study treatment and is followed for comparison.

One site, in Fredericton

2 groups
One site, in Fredericton
Recruiting

Official title: Diabetes, Insulin, Gut, Enteric Supplementation Trial

Gestational Diabetes Mellitus (GDM) · University of New Brunswick

Testing Rezpegaldesleukin against a placebo for type 1 diabetes mellitus

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There are 2 groups in this study. Group A receives Rezpegaldesleukin. Group B, the placebo group, receives Placebo.

One site, in Vancouver

Phase 2
2 groups
One site, in Vancouver
Recruiting

Official title: Rezpegaldesleukin (NKTR-358) in New Onset Type 1 Diabetes Mellitus

Type 1 Diabetes Mellitus · National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Comparing Semaglutide with Nicotine replacement for type 2 diabetes mellitus

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There are 2 groups in this study. Group A receives one or more of: Semaglutide and Nicotine replacement. Group B, the comparison group, receives Nicotine replacement.

One site, in Ottawa

Phase 3
2 groups
One site, in Ottawa
Recruiting

Official title: Semaglutide for Smoking Cessation in Patients With Diabetes

Diabetes Mellitus, Type 2 · Ottawa Heart Institute Research Corporation

Testing DPP System (Insulin Pump and Continuous for type 1 diabetes mellitus

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Everyone in this study is in one group and receives DPP System (Insulin Pump and Continuous Glucose Monitoring Platform).

One site, in Toronto

Early Phase 1
1 group
One site, in Toronto
Recruiting

Official title: Simultaneous Measurement and Responsive Treatment - Part 2

Type 1 Diabetes Mellitus · ClinSurge Research

Testing Low-carbohydrate breakfast for type 2 diabetes

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There are 2 groups in this study. Group A receives Low-carbohydrate breakfast. Group B, the comparison group, receives Low-fat Control breakfast.

One site, in Kelowna

2 groups
One site, in Kelowna
Recruiting

Official title: UBC Breakfast Study 2.0

Type 2 Diabetes · University of British Columbia

Comparing Fasted Exercise with Postprandial Exercise for type 1 diabetes mellitus

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There are 2 groups in this study. Group A receives Fasted Exercise. Group B, the comparison group, receives Postprandial Exercise.

One site, in Edmonton

2 groups
One site, in Edmonton
Recruiting

Official title: Fasted Exercise Training in Type 1 Diabetes (FED-T1D)

Diabetes Mellitus, Type 1 · University of Alberta

Comparing Zenagamtide with Insulin glargine U-100 for type 2 diabetes

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There are 2 groups in this study. Group A receives Zenagamtide. Group B, the comparison group, receives Insulin glargine U-100.

Sites in Kelowna, Calgary and 7 more cities

Phase 3
2 groups
Sites in Calgary, Edmonton and 7 more cities
Recruiting

Official title: AMBITION 7: A Research Study Investigating How Well Zenagamtide Lowers Blood Sugar and Body Weight Compared to Insulin Glargine in People With Type 2 Diabetes and Increased Risk of Diseases That Affect the Heart and Blood Vessels Treated With 1-3 Other Diabetes Medications

Type 2 Diabetes · Novo Nordisk A/S

Testing Educational Video for type 2 diabetes

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Everyone in this study is in one group and receives Educational Video.

One site, in Mississauga

1 group
One site, in Mississauga
Recruiting

Official title: Integrating Educational Videos Into Skills-Based Nutrition Programs to Reduce Type 2 Diabetes Risk in Peel

Type 2 Diabetes · University of Toronto

Testing Elecoglipron against a placebo for type 2 diabetes mellitus

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There are 3 groups in this study. Groups A and B receive Elecoglipron. Group C, the placebo group, receives Placebo.

Sites in Brampton, North York and 6 more cities

Phase 3
3 groups
Sites in Surrey, Vancouver and 5 more cities
Recruiting

Official title: A Phase III Study to Investigate the Efficacy and Safety of Elecoglipron Compared With Placebo in Adults With Type 2 Diabetes Mellitus on Background Insulin

Type 2 Diabetes Mellitus · AstraZeneca

Comparing Time-restricted eating with Standard lifestyle for type 2 diabetes

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There are 2 groups in this study. Group A receives Time-restricted eating. Group B, the comparison group, receives Standard lifestyle.

One site, in Toronto

2 groups
One site, in Toronto
Recruiting

Official title: Time Restricted-EAting for Type 2 Diabetes and MEtabolic Health: the TEA TIME Trial

Type 2 Diabetes · Mount Sinai Hospital, Canada

Comparing AMPK Charge+® with AMPK Charge+® with semaglutide for prediabetes / type 2 diabetes

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There are 2 groups in this study. Group A receives AMPK Charge+®. Group B, the comparison group, receives AMPK Charge+® with semaglutide.

One site, in London

2 groups
One site, in London
Recruiting

Official title: A Clinical Trial to Examine the Efficacy and Safety of an Investigational Product With and Without Use of Semaglutide on Glycemic Response in Adults With Prediabetes or Type 2 Diabetes

Prediabetes / Type 2 Diabetes · QuickSilver Scientific

Comparing Step Count tracking and goals with Dyadic coping intervention for type 2 diabetes

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There are 2 groups in this study. Group A, the comparison group, receives Step Count tracking and goals. Group B receives Step Count tracking and goals and Dyadic coping intervention.

3 sites in Montreal

2 groups
3 sites in Montreal
Recruiting

Official title: Helping Couples Communicate Better: Does This Help Persons With Type 2 Diabetes Respond Better to a Step Count Prescription?

Type 2 Diabetes · McGill University Health Centre/Research Institute of the McGill University Health Centre

Testing QX1206 for type 2 diabetes mellitus (T2DM)

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Everyone in this study is in one group and receives QX1206.

One site, in Toronto

Phase 1
1 group
One site, in Toronto
Recruiting

Official title: A Phase 1b Study of QX1206 in T2DM Patients With NAFLD

Type 2 Diabetes Mellitus (T2DM) · 1Globe Health Institute

Testing Missed Dose with Missed Dose + 15min walk (MISS+EX) for type 1 diabetes mellitus

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Everyone in this study is in one group, which receives one or more of: Control (CON), Missed Dose (MISS) and Missed Dose + 15min walk (MISS+EX).

One site, in Montreal

1 group
One site, in Montreal
Recruiting

Official title: Physical Activity to Prevent and Treat Hyperglycemia From a Mistimed Bolus Insulin Dose

Type 1 Diabetes Mellitus · Jane Yardley

Testing Polygenic Risk Score for type 2 diabetes mellitus

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There are 2 groups in this study. Group A, the comparison group, receives Polygenic Risk Score. Group B receives no study treatment and is followed for comparison.

2 sites in Montreal

2 groups
2 sites in Montreal
Recruiting

Official title: Clinical Utility of a Genomic Predictor Test on the Management of Cardiorenal Complications of Type 2 Diabetes

Diabetes Mellitus, Type 2 · Optithera

Comparing 3 approaches for type 1 diabetes mellitus

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There are 3 groups in this study. Groups A, B and C, the comparison group, receive one or more of: MTX228 and DEXCOM G6.

One site, in Edmonton

Phase 2
3 groups
One site, in Edmonton
Recruiting

Official title: An Adaptive Design Study of MTX228

Type 1 Diabetes Mellitus · University of Alberta

Testing Boost Original meal replacement shake for type 2 diabetes

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Everyone in this study is in one group and receives Boost Original meal replacement shake.

One site, in Ottawa

1 group
One site, in Ottawa
Recruiting

Official title: Pancreatic Insulin Production Capacity (PIPC) - a Feasibility Study

Type 2 Diabetes · Ottawa Hospital Research Institute

Comparing 3 approaches for type 2 diabetes mellitus

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There are 4 groups in this study. Group A receives Early (7:00 - 16:00) TRE. Group B receives Mid (9:30 - 18:30) TRE. Group C receives Late (12:00 - 21:00) TRE. …and 1 more groups.

One site, in Toronto

4 groups
One site, in Toronto
Recruiting

Official title: Time-restricted Eating, Window Timing, Type 2 Diabetes Status and Sex on Glycemic Control

Diabetes Mellitus, Type 2 · University of Toronto

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Concord provides information support only. Trial listings come from public registries; eligibility is always determined by the trial site and your care team.