Comparing 3 approaches for satiety satiation
Official title: The Chocolate Almond Study - Relating Chewing to Satiation and Postprandial Response
The Impact of Almond Size in a White Chocolate Matrix on Satiation, Postprandial Glycemia & Lipemia, Chewing Exertion, Eating Rate, and Product Liking: A Randomized Crossover Trial
- 3 groups
- One site, in Guelph
- Recruiting
Interventions
- Other intervention
200 g serving of white chocolate-based confection product
200 g serving of white chocolate-based confection product
Canadian Sites (1)
1 of 1 recruiting
- Recruiting
Department of Human Health Sciences
Guelph, Ontario
Eligibility Criteria
See who this study is looking for33 criteria
The trial’s own eligibility text, word for word from the registry. Only the trial site can say who takes part.
Inclusion
- +BMI between 18.5-27.9 kg/m\^2 or waist circumference less than 88 cm
- +No known food allergies or sensitivities
- +Non-restrained eaters based on the Three Factor Eating Questionnaire
- +No history of gastrointestinal diseases that may interfere with eating behaviour or digestion
- +Not on medications that affect appetite, digestion, blood sugar regulation, saliva production, or chewing
- +Stable medication use
- +Not gained or lost significant weight during the past 3 months
- +Regular monthly menstrual cycles
- +Not pregnant, lactating, or post-menopausal
- +Non-smokers
Exclusion
- −Any food allergies, intolerance, or sensitivities
- −Any life-threatening allergy
- −Diabetes or other metabolic disorders affecting glycemia and overall cardiometabolic health
- −Participation in another clinical trialInterventional studyA study where participants are given something to see what happens.Read more →
- −Alcohol consumption more than 14 drinks per week
- −Regular use of recreational drugs (e.g., marijuana, ecstasy, magic mushrooms)
- −Restrained eater as defined by \> 15 on the Three-Factor Eating Questionnaire
- −Unusual sleep patterns
- −Irregular breakfast consumption
- −Recent weight changes or intended weight loss or gain or having lost or gained \>10% of body weight within the last 6 months
- −Experiences dry mouth, in general or due to medication side effectsSide effectAn unwanted effect thought to be caused by the treatment itself.Read more →
- −Diagnosed with Sjogren's Syndrome (autoimmune condition linked to severe dry mouth)
- −Inability to adhere to study protocols
- −Not comfortable providing finger prick blood samples
- −Avoids consuming almonds or chocolate
- −Has temporomandibular joint disorder (TMJ)
- −Has or history or oral cancer
- −Avoids eating hard foods for concerns of dental fractures or for general oral health
- −Individuals with dentures, braces, Invisalign, or other dental implants that cause difficulty chewing
- −Pregnant or breastfeeding
- −Using medications known to affect appetite, digestion, blood sugar regulation, lipids, or chewing (excluding oral contraceptives)
- −Recent dental or jaw surgery
- −Smokers or those with a smoking history or more than 10 years
In plain language
Assembled directly from this trial’s registry record. Every sentence traces to a field below — nothing here is generated or interpreted.
What this study is
This study is investigating how something functions in the body, rather than testing a treatment directly.
This study is not organised into the usual phase numbers — that is common for device, behavioural, and diagnostic research.
From the trial registry
Built from these fields:
- designModule.designInfo.primaryPurpose
- designModule.phases
Who receives what
There are 3 groups in this study.
Groups A, B and C receive 200 g serving of white chocolate-based confection product.
Registry label: A: White chocolate with whole almonds · B: White chocolate without almonds · C: White chocolate with chopped almonds
From the trial registry
Built from these fields:
- armsInterventionsModule.armGroups[].label
- armsInterventionsModule.armGroups[].type
- armsInterventionsModule.armGroups[].interventionNames
How the study is run
Which group you would be placed in is decided by chance, like a coin flip — not by you and not by your doctor.
Neither you nor the study team would know which group you are in until the study ends.
From the trial registry
Built from these fields:
- designModule.designInfo.allocation
- designModule.designInfo.maskingInfo.masking
Is there a placebo?
This study does not list a placeboPlaceboA dummy treatment with no active medicine, used for comparison.Read more → group.
From the trial registry
Built from these fields:
- armsInterventionsModule.armGroups[].type
- armsInterventionsModule.armGroups[].interventionNames
Who the study is looking for
The study lists an age range of 18 years to 45 years.
The study lists female participants only.
The study accepts healthy volunteersHealthy volunteerSomeone without the condition being studied who takes part anyway.Read more → as well as people with the condition.
These are the criteria the study lists. Only the trial siteTrial siteA hospital or clinic where a study is actually run.Read more → can decide whether someone can take part.
From the trial registry
Built from these fields:
- eligibilityModule.minimumAge
- eligibilityModule.maximumAge
- eligibilityModule.sex
- eligibilityModule.healthyVolunteers
How big and how long
The study aims to enrol about 35 people.
The study is currently expected to finish around May 2026.
The main measurement is taken over: BaselineBaselineYour starting measurements, taken before treatment begins.Read more →.
From the trial registry
Built from these fields:
- designModule.enrollmentInfo.count
- statusModule.completionDateStruct.date
- outcomesModule.primaryOutcomes[].timeFrame
What the study measures
Satiation — measured over BaselineBaselineYour starting measurements, taken before treatment begins.Read more →.
From the trial registry
Built from these fields:
- outcomesModule.primaryOutcomes[].measure
- outcomesModule.primaryOutcomes[].timeFrame
Source: NCT07065461 on ClinicalTrials.gov. The full registry text is further down this page — this summary never replaces it.
Not medical advice. What do these terms mean?
What is being tested — in plain terms
About 200 g serving of white chocolate-based confection productOther
200 g serving of white chocolate-based confection product
From the trial registry — its own words, unedited.
What a other is here: An intervention the registry did not place in another category.
Read the full explanation → · in clinical review
Common questions
Answered from this trial’s registry record. Where the record doesn’t say, these answers say so rather than filling the gap.
Am I eligible for this trial?
Only the trial siteTrial siteA hospital or clinic where a study is actually run.Read more → can decide whether someone can take part. Concord cannot make that determination, and neither can any tool that has not examined you.
What the study lists: an age range of 18 years to 45 years.
The full inclusionInclusion criteriaThe things you must have or be for a study to consider you.Read more → and exclusion criteriaExclusion criteriaThe things that would prevent someone from taking part.Read more → are published on this page, exactly as the study team wrote them.
The useful next step is to bring this trial to your doctor. Answering a few questions first gives them something concrete to review.
From the trial registry
- eligibilityModule.minimumAge
- eligibilityModule.maximumAge
- eligibilityModule.eligibilityCriteria
Is there a placebo?
This study does not list a placeboPlaceboA dummy treatment with no active medicine, used for comparison.Read more → group.
From the trial registry
- armsInterventionsModule.armGroups[].type
Would I know which treatment I am getting?
Neither you nor the study team would know which group you are in until the study ends.
Which group you would be placed in is decided by chance, like a coin flip — not by you and not by your doctor.
From the trial registry
- designModule.designInfo.maskingInfo.masking
- designModule.designInfo.allocation
Who can join?
The study lists an age range of 18 years to 45 years.
It lists female participants only.
It accepts healthy volunteersHealthy volunteerSomeone without the condition being studied who takes part anyway.Read more → as well as people with the condition.
Only the trial siteTrial siteA hospital or clinic where a study is actually run.Read more → can confirm whether a particular person can take part.
From the trial registry
- eligibilityModule.minimumAge
- eligibilityModule.maximumAge
- eligibilityModule.sex
- eligibilityModule.healthyVolunteers
How long would this take?
The study's main measurement is taken over: BaselineBaselineYour starting measurements, taken before treatment begins.Read more →.
The study as a whole is currently expected to finish around 2026-05.
How long any one person takes part can differ from the study length. The study team can tell you what the schedule looks like in practice.
From the trial registry
- outcomesModule.primaryOutcomes[].timeFrame
- statusModule.completionDateStruct.date
How many people are taking part?
The study aims to enrol about 35 people.
From the trial registry
- designModule.enrollmentInfo.count
Where is this happening?
This study lists one location: Guelph, Ontario, Canada.
Sites can open and close during a study, so confirm with the team before travelling.
From the trial registry
- trial_locations
About This Trial
The goal of this clinical trial is to relate chewing behaviours to food intake and postprandial response for a texturally complex food matrix (almonds in white chocolate) in healthy young females. The main questions it aims to answer are: * Does the presence or preparation of almonds (whole versus chopped) influence satiation, i.e., the amount consumed at an ad libitum meal? * What is the correlation between chewing behaviour, satiation, and changes in postprandial glucose, triacylglycerols, and satiety ratings? Participants will attend the research centre fasted on three occasions to consume an ad libitum meal, complete questionnaires, and provide fasting and postprandial finger prick blood samples.
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See if this trial could fit youThis page is for informational purposes only and does not constitute medical advice. Clinical trial eligibility can only be determined by the trial site after proper screening. Trial information is sourced from ClinicalTrials.gov and may not reflect the most current status. Always consult your healthcare provider before making decisions about clinical trial participation.