Schizophrenia Clinical Trials

Trials for someone you care about with schizophrenia.

Mental Health

Recruiting Drug Device Behavioral Older adults Healthy volunteers

20 trials

Testing d-DBT for clinical high risk for psychosis (CHR)

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One site, in Toronto

Recruiting

Official title: Digital Dialectical Behavioural Therapy (d-DBT) for Youth at Clinical High Risk (CHR) for Psychosis

Clinical High Risk for Psychosis (CHR) · Centre for Addiction and Mental Health

Testing Clozapine for schizophrenia

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One site, in Toronto

RecruitingPHASE4

Official title: Switching From Twice-Daily to Once-Daily Clozapine Dosing in Schizophrenia

Schizophrenia · Centre for Addiction and Mental Health

Testing N-Acetylcysteine against a placebo for prodromal schizophrenia

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One site, in Toronto

Recruiting

Official title: Effects of NAC on Symptoms of CHR Patients

Prodromal Schizophrenia · Centre for Addiction and Mental Health

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Testing Cognitive Enhancement Therapy for psychosis

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One site, in Halifax

Recruiting

Official title: Piloting of an Intervention to Reduce Problematic Alcohol Use in Early Phase Psychosis Patients

Psychosis · Nova Scotia Health Authority

Comparing 3 approaches for schizophrenia

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One site, in Toronto

Recruiting

Official title: Neuromodulation for Schizophrenia

Schizophrenia · Scion NeuroStim

Comparing 3 approaches for schizophrenia

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Sites in Scarborough Village and Whitby

Recruiting

Official title: Outcomes From Remediation and Behavioural Intervention Techniques

Schizophrenia · University of Toronto

Testing Intranasal insulin for schizophrenia

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One site, in Toronto

Recruiting

Official title: Does Abnormal Insulin Action in the Brain Underlie Cognitive and Metabolic Dysfunction in Schizophrenia

Schizophrenia · Centre for Addiction and Mental Health

Testing KarXT for psychosis associated with Alzheimer's disease

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Sites in Calgary, Hamilton and 3 more cities

RecruitingPHASE3

Official title: Open-Label Extension Study to Assess the Long-Term Safety and Tolerability of KarXT in Subjects With Psychosis Associated With Alzheimer's Disease (ADEPT-3)

Psychosis Associated With Alzheimer's Disease · Karuna Therapeutics, Inc., a Bristol Myers Squibb company

Testing KarXT against a placebo for psychosis associated with Alzheimer's disease

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Sites in Calgary, Hamilton and 4 more cities

RecruitingPHASE3

Official title: A Study to Assess Efficacy and Safety of KarXT for the Treatment of Psychosis Associated With Alzheimer's Disease (ADEPT-2)

Psychosis Associated With Alzheimer's Disease · Karuna Therapeutics, Inc., a Bristol Myers Squibb company

Comparing Magnetic Seizure Therapy with Electroconvulsive Therapy for treatment resistant schizophrenia

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Sites in Toronto and Vancouver

Recruiting

Official title: Magnetic Seizure Therapy for Schizophrenia - Trial

Treatment Resistant Schizophrenia · Centre for Addiction and Mental Health

Testing ML-007C-MA against a placebo for psychosis associated with Alzheimer's disease

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Sites in Brampton, Lévis and 2 more cities

RecruitingPHASE2

Official title: A Study to Assess the Efficacy and Safety of ML-007C-MA for the Treatment of Alzheimer's Disease Psychosis

Psychosis Associated With Alzheimer's Disease · MapLight Therapeutics

Testing Metformin for psychosis

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Sites in Halifax and St. John's

RecruitingPHASE4

Official title: Cannabis Potency Effects on Brain White Matter in Early Phase Psychosis

Psychosis · Nova Scotia Health Authority

Testing KarXT for schizophrenia

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Sites in Calgary, Edmonton and 3 more cities

RecruitingPHASE3

Official title: A Study to Evaluate the Long-term Safety and Tolerability of KarXT and KarX-EC for the Treatment of Schizophrenia and Autism-Related Irritability in Adolescents, Respectively

Schizophrenia · Karuna Therapeutics, Inc., a Bristol Myers Squibb company

Testing REFLECT: REFlecting on and Learning to for schizophrenia spectrum & other psychotic disorders

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One site, in Scarborough Village

Recruiting

Official title: REFLECT: A Novel Group-Based Compassion-Focussed Cognitive Behavioural Approach to Core Beliefs in Psychosis

Schizophrenia Spectrum & Other Psychotic Disorders · University of Toronto

Testing maCBT for schizophrenia

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2 sites in Halifax

Recruiting

Official title: Skills for Wellness

Schizophrenia · Nova Scotia Health Authority

Testing Medium chain triglyceride oil for first episode psychosis

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One site, in Sherbrooke

Recruiting

Official title: Recovery With Exogenous Ketones and Antipsychotics

First Episode Psychosis · Université de Sherbrooke

Testing Active Intermittent Theta Burst against a placebo for clinical high risk for psychosis (CHR)

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One site, in Verdun

Recruiting

Official title: Accelerated Neuromodulation Therapy and Neurocomputational Biomarkers in Individuals at Clinical High Risk for Psychosis

Clinical High Risk for Psychosis (CHR) · Douglas Mental Health University Institute

Testing Risperidone with Olanzapine for schizophrenia and related disorders

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One site, in Toronto

RecruitingPHASE4

Official title: "Extended" (Alternate Day) Antipsychotic Dosing

Schizophrenia and Related Disorders · Centre for Addiction and Mental Health

Testing Neuronavigated Intermittent Theta Burst against a placebo for schizophrenia and predominant negative symptoms

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Sites in Montreal, Québec and 1 more city

Recruiting

Official title: Accelerated Neuromodulation Therapy for Negative Symptoms of Schizophrenia

Schizophrenia and Predominant Negative Symptoms · Douglas Mental Health University Institute

Testing Action-Based Cognitive Remediation for psychosis

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Sites in Halifax and St. John's

Recruiting

Official title: Effects of Action-Based Cognitive Remediation on Substance Misuse in Early Phase Psychosis

Psychosis · Nova Scotia Health Authority

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Concord provides information support only. Trial listings come from public registries; eligibility is always determined by the trial site and your care team.